dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050612
Uniprot Accession E9PUQ8; E9PUQ8_MOUSE;
Genbank Protein ID NP_808314.2;
Genbank Nucleotide ID NM_177646.3;
Protein Name Diacylglycerol kinase
Protein Synonyms/Alias
Gene Name Dgkd
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
44QKLIRKVSTSGQIRQPhosphoSitePlus;curated22135298; 23684622; 21183079; 25338131
45KLIRKVSTSGQIRQKPhosphoSitePlus;curated22135298; 23684622; 21183079
46LIRKVSTSGQIRQKTPhosphoSitePlus22135298
697KLVSKGLSLGSSASLPhosphoSitePlus;curated22135298; 21183079
700SKGLSLGSSASLPPGPhosphoSitePlus;curated22135298; 21183079
733VRAGMSGSLPGGSVIPhosphoSitePlus22135298
967CELSRPPSFSLHPEIPhosphoSitePlus22135298
1214GIKELSRSSPAAEA-PHOSIDA;PhosphoSitePlus21081558; 22135298
Sequence
(Fasta)		MAAAAGAPPP GPPQPPPPPP PEESSDSEPE AEPGSPQKLI RKVSTSGQIR QKTILKEGML 60
TKQNNSFQRS KRRYFKLRGR TLYYAKTAKS IIFDEVDLTD ASVAESSTKN VNNSFTVITP 120
CRKLILCADN RKEMEDWIAA LKTVQNKEHF EPTQYSMDHF SGMHNWYACS HARPTYCNVC 180
REVLSGVTSH GLSCEVCKFK AHKRCAVRAT SNCKWTTLAS IGKDIIEDED GIAMPHQWLE 240
GNLPVSAKCI VCDKTCGSVL RLQDWRCLWC KAMVHTSCKE SLVMKCPLGL CKVSVIPPTA 300
LNSIDSDGFW KATCPPSCTS PLLVFVNSKS GDNQGVKFLR RFKQLLNPAQ VFDLMNGGPH 360
LGLRLFQKFD TFRILVCGGD GSVGWVLSEI DSLNLHKQCQ LGVLPLGTGN DLARVLGWGS 420
ACDDDTQLPQ ILAKLERAST KMLDRWSVMA YETKLPRQAS SSTVTEDFSE DSEVQQILFY 480
EDSVAAHLSK ILTSDQHSVV ISSAKVLCET VKDFVARVGK AYEKTTESSQ ESEVMAKKCS 540
VLKEKLDSLL KTLDDESQAS SSLSNPPPTI AEEAEDGDGS GNICSSTGDH LVGSACPSRP 600
QIFRPREQLM LRANSLKKAI RQIIEHTEKA VDEQNAQTQE QQGFVLGLSE SEKKDLKTDN 660
RVCTSSVHSE SCVIAKGRSQ RKASRAPCEK LVSKGLSLGS SASLPPGTGS RDSLPALNTK 720
ILYPSVRAGM SGSLPGGSVI SRLLINADPF NAEPENLEYY TEKCVMNNYF GIGLDAKISL 780
DFNNKRDEHP EKCRSRTKNM MWYGVLGTKE LLHRTYRNLE QKVLLECDGR PIPLPSLQGI 840
AVLNIPSYAG GTNFWGGTKE DDTFAAPSFD DKILEVVAVF GSMQMAVSRV IKLQHHRIAQ 900
CRTVKISILG DEGVPVQVDG EAWIQPPGYI RIVHKNRAQT LTRDRAFENT LKSWEDKQKC 960
ELSRPPSFSL HPEILSEEEA TQMDQFGQAA GGLIHSIREI AQSHRAMEQE LAHAVNASSK 1020
AMERVYGKPR TAEGLNCSFV LEMVNNIRAL RSETELLLAG KMALQLDPPQ KERLGAALIE 1080
MDQQLRKLTD TPWLCQPLEP GEEESLQQNV MLDLTKRSRS GKFRLVTKFK KEKNNKNKEV 1140
HSNLGGPVHL WGTEEVAAWL EHLSLCEYKD IFTRHDIRGS ELLHLERRDL KDLGVTKVGH 1200
MKRILCGIKE LSRSSPAAEA 1221
Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000756--Diacylglycerol_kin_accessory
IPR001206--Diacylglycerol_kinase_cat_dom
IPR016064--NAD/diacylglycerol_kinase
IPR002219--PE/DAG-bd
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR001660--SAM
IPR013761--SAM/pointed
PROSITE

PS50146--DAGK
PS50003--PH_DOMAIN
PS50105--SAM_DOMAIN
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2
Pfam

PF00130--C1_1
PF00609--DAGK_acc
PF00781--DAGK_cat
PF00169--PH
PF07647--SAM_2
Gene Ontology

GO:0005737--C:cytoplasm
GO:0016023--C:cytoplasmic membrane-bounded vesicle
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004143--F:diacylglycerol kinase activity
GO:0046982--F:protein heterodimerization activity
GO:0042803--F:protein homodimerization activity
GO:0046339--P:diacylglycerol metabolic process
GO:0035556--P:intracellular signal transduction
GO:0051260--P:protein homooligomerization
GO:0007205--P:protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0010033--P:response to organic substance