dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050603
Uniprot Accession E9PUD2; E9PUD2_MOUSE;
Genbank Protein ID NP_690029.2;
Genbank Nucleotide ID NM_152816.3;
Protein Name Dynamin-1-like protein
Protein Synonyms/Alias
Gene Name Dnm1l
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
95WKNSRHLSKGVEAEEPhosphoSitePlus22135298
548GSRDKVPSAGGGIGDPhosphoSitePlus;curated22135298; 23684622
Sequence
(Fasta)
MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL LPRGTGVVTR 60
RPLILQLVHV SPEDKRKTTG EENDPATWKN SRHLSKGVEA EEWGKFLHTK NKLYTDFDEI 120
RQEIENETER ISGNNKGVSP EPIHLKVFSP NVVNLTLVDL PGMTKVPVGD QPKDIELQIR 180
ELILRFISNP NSIILAVTAA NTDMATSEAL KISREVDPDG RRTLAVITKL DLMDAGTDAM 240
DVLMGRVIPV KLGIIGVVNR SQLDINNKKS VTDSIRDEYA FLQKKYPSLA NRNGTKYLAR 300
TLNRLLMHHI RDCLPELKTR INVLAAQYQS LLNSYGEPVD DKSATLLQLI TKFATEYCNT 360
IEGTAKYIET SELCGGARIC YIFHETFGRT LESVDPLGGL NTIDILTAIR NATGPRPALF 420
VPEVSFELLV KRQIKRLEEP SLRCVELVHE EMQRIIQHCS NYSTQELLRF PKLHDAIVEV 480
VTCLLRKRLP VTNEMVHNLV AIELAYINTK HPDFADACGL MNNNIEEQRR NRLARELPSA 540
GSRDKVPSAG GGIGDGGQEP TTGNWRGMLK TSKAEELLAE EKSKPIPIMP ASPQKGHAVN 600
LLDVPVPVAR KLSAREQRDC EVIERLIKSY FLIVRKNIQD SVPKAVMHFL VNHVKDTLQS 660
ELVGQLYKSS LLDDLLTESE DMAQRRKEAA DMLKALQGAS QIIAEIRETH LW 713
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0342--GTP-binding
KW-0547--Nucleotide-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR030556--DNM1L
IPR000375--Dynamin_central
IPR001401--Dynamin_GTPase
IPR019762--Dynamin_GTPase_CS
IPR022812--Dynamin_SF
IPR030381--G_DYNAMIN_dom
IPR003130--GED
IPR020850--GED_dom
IPR027417--P-loop_NTPase

PROSITE

PS00410--G_DYNAMIN_1
PS51718--G_DYNAMIN_2
PS51388--GED

Pfam

PF01031--Dynamin_M
PF00350--Dynamin_N
PF02212--GED

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0043231--C:intracellular membrane-bounded organelle
GO:0016020--C:membrane
GO:0005874--C:microtubule
GO:0005741--C:mitochondrial outer membrane
GO:0005739--C:mitochondrion
GO:0048471--C:perinuclear region of cytoplasm
GO:0005777--C:peroxisome
GO:0043234--C:protein complex
GO:0005525--F:GTP binding
GO:0003924--F:GTPase activity
GO:0042802--F:identical protein binding
GO:0042803--F:protein homodimerization activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0003374--P:dynamin polymerization involved in mitochondrial fission
GO:0061025--P:membrane fusion
GO:0000266--P:mitochondrial fission
GO:0043653--P:mitochondrial fragmentation involved in apoptotic process
GO:0090149--P:mitochondrial membrane fission
GO:0070584--P:mitochondrion morphogenesis
GO:0070266--P:necroptotic process
GO:0016559--P:peroxisome fission
GO:0043065--P:positive regulation of apoptotic process
GO:2001244--P:positive regulation of intrinsic apoptotic signaling pathway
GO:0090141--P:positive regulation of mitochondrial fission
GO:0050714--P:positive regulation of protein secretion
GO:0090200--P:positive regulation of release of cytochrome c from mitochondria
GO:0051289--P:protein homotetramerization
GO:0070585--P:protein localization to mitochondrion
GO:0010821--P:regulation of mitochondrion organization
GO:1903146--P:regulation of mitophagy
GO:1900063--P:regulation of peroxisome organization
GO:0032459--P:regulation of protein oligomerization
GO:0001836--P:release of cytochrome c from mitochondria