dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0050599
Uniprot Accession E9PUA3; E9PUA3_MOUSE;
Genbank Protein ID NP_001127856.1;
Genbank Nucleotide ID NM_001134384.1;
Protein Name IQ motif and SEC7 domain-containing protein 1
Protein Synonyms/Alias
Gene Name Iqsec1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 8
PositionPeptidesSourceReferences ( PMIDs )
923AGKRGRRSSAGSLESPhosphoSitePlus22135298
924GKRGRRSSAGSLESNPhosphoSitePlus;curated22135298; 26160508
927GRRSSAGSLESNVEGPhosphoSitePlus;curated22135298; 26160508
930SSAGSLESNVEGSIIPhosphoSitePlus;curated22135298; 26160508; 21183079
935LESNVEGSIISSPHMPhosphoSitePlus22135298
938NVEGSIISSPHMRRRcurated26160508; 21183079
939VEGSIISSPHMRRRAPhosphoSitePlus;curated22135298; 21183079
973LLGSLFGSRRGKPPPPhosphoSitePlus22135298
Sequence
(Fasta)
MACRRRYFVE GEAPSSETGT SLDSPSAYHQ GPLVPGSSLS PDHYEHTSVG AYGLYAGPGP 60
QQRTRRPRLQ HSTSVLRKQA EEEAIKRSRS LSESYELSSD LQDKQVEMLE RKYGGRLVTR 120
HAARTIQTAF RQYQMNKNFE RLRSSMSENR MSRRIVLSNM RMQFSFEGPE KVHSSYFEGK 180
QVSVTNDGSQ LGALVPSECG DLSDPALKSP APSSDFADAI TELEDAFSRQ VKSLAESIDD 240
ALNCRSLHSE EVPASDTARA RDTEPKPGLH GMDHRKLDEM TASYSDVTLY IDEEELSPPL 300
PLSQAGDRPS STESDLRLRS GGAAQDYWAL AHKEDKADTD TSCRSTPSLE RPEPRLRVEH 360
LPLLTIEPPS DSSVELSDRS DRSSLKRQSA YERSLGGQQG SPKHGPHGGP PKGLPREEPE 420
LRPRPPRPLE SHLAINGSAN RQSKSESDYS DGDNDSINST SNSNDTINCS SESSSRDSLR 480
EQTLSKQTYH KETRNSWDSP AFSNDVIRKR HYRIGLNLFN KKPEKGIQYL IERGFVPDTP 540
VGVAHFLLQR KGLSRQMIGE FLGNRQKQFN RDVLDCVVDE MDFSAMELDE ALRKFQAHIR 600
VQGEAQKVER LIEAFSQRYC VCNPGVVRQF RNPDTIFILA FAIILLNTDM YSPNVKPERK 660
MKLEDFVKNL RGVDDGEDIP RETLIGIYER IRKRELKTNE DHVSQVQKVE KLIVGKKPIG 720
SLHHGLGCVL SLPHRRLVCY CRLFEVPDPN KPQKLGLHQR EIFLFNDLLV VTKIFQKKKN 780
SVTYSFRQSF SLYGMQVLLF ENQYYPNGIR LTSAVPGADI KVLINFNAPN PQDRKKFTDD 840
LRESVAEVQE MEKHRIESEL EKQKGVVRPS MSQCSSLKKE SGNGTLSRAC LDDSYASGEG 900
LKRSALSSSL RDLSEAGKRG RRSSAGSLES NVEGSIISSP HMRRRATSTR ECPSRPPQPV 960
PNSSSLLGSL FGSRRGKPPP QAHPPSAPPP APPHAHHPGP SEGPLHGHHA QYCHAQQNPP 1020
PYHHHHHYHP PPHLQHTHQY HHGPHGGHPP YGAHAHSHPP LPTAHPGHAG HSAHHHGQPP 1080
APPPPTSSKA KPSGISTVV
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000048--IQ_motif_EF-hand-BS
IPR030737--IQSEC1
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR023394--Sec7_alpha_orthog
IPR000904--Sec7_dom

PROSITE

PS50096--IQ
PS50190--SEC7

Pfam

PF16453--IQ_SEC7_PH
PF01369--Sec7

Gene Ontology

GO:0016020--C:membrane
GO:0005086--F:ARF guanyl-nucleotide exchange factor activity
GO:0030036--P:actin cytoskeleton organization
GO:0032012--P:regulation of ARF protein signal transduction