dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050320
Uniprot Accession E1U8D0; SOGA1_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Protein SOGA1
Protein Synonyms/Alias SOGA family member 1;Suppressor of glucose by autophagy;Suppressor of glucose, autophagy-associated protein 1;
Gene Name Soga1
Gene Synonyms/Alias Soga;
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)		 Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner.
Phosphorylation Sites
 dbPAF PTMs: 14
PositionPeptidesSourceReferences ( PMIDs )
121LDRPREHSLKKRGTRPhosphoSitePlus;curated22135298; 25338131
924TGLKRTKSVSSMSEFPhosphoSitePlus;curated22135298; 21183079
926LKRTKSVSSMSEFESPhosphoSitePlus22135298
927KRTKSVSSMSEFESLcurated21183079
929TKSVSSMSEFESLLDPhosphoSitePlus;curated22135298; 21183079
1015TGIRVYYSPPVARRLPhosphoSitePlus;curated22135298; 21183079; 25338131
1117CVRQAMRSGSLERKVPhosphoSitePlus22135298
1119RQAMRSGSLERKVKNPhosphoSitePlus22135298
1195RIERPCCSPKYGSPKPhosphoSitePlus22135298
1300NVCGRAPSPTTAAGEPhosphoSitePlus;curated22135298; 23684622; 25338131
1302CGRAPSPTTAAGEEScurated23684622
1303GRAPSPTTAAGEESCPhosphoSitePlus22135298
1309TTAAGEESCKKPEPLPhosphoSitePlus22135298
1317CKKPEPLSPASYHQPPhosphoSitePlus;curated22135298; 25338131
Sequence
(Fasta)		MLEMRDVYME EDVYQLQELR QQLDQASKTC RILQYRLRKA ERRSLRAAQT GQVDGELIRG 60
LEQDVKVSKD ISMRLHKELE VVEKKRMRLE EENEGLRQRL IETELAKQVL QTELDRPREH 120
SLKKRGTRSL GKTDKKPTAQ EDSADLKCQL HFAKEESALM CKKLTKLAKE NDSMKEELLK 180
YRSLYGDLDA ALSAEELADA PHSRETELKV HLKLVEEEAN LLSRRIVELE VENRGLRAEM 240
DDMKDHGGGG GPEARLAFSS LGGECGESLA ELRRHLQFVE EEAELLRRSS AELEDQNKLL 300
LNELAKYRSE HELDVTLSED SCSVLSEPSQ EELAAAKLQI GELSGKVKKL QYENRVLLSN 360
LQRCDLASCQ STRPMLETDA EAGDSAQCVP APLGETLEPH AARLCRAREA EALPGLREQA 420
ALVSKAIDVL VADANGFSVG LRLCLDNECA DLRLHEAPDN SEGPRDAKLI HAILVRLSVL 480
QQELNAFTRK ADVALGSSGK EQPEPFPALP ALGSQGPAKE IMLSKDLGSD FQPPDFRDLL 540
EWEPRIREAF RTGDLESKPD PSRNFRPYRA EDNDSYASEI KDLQLVLAEA HDSLRGLQEQ 600
LSQERQLRKE EADSFNQKMV QLKEDQQRAL LRREFELQSL SLQRRLEQKF WSQEKNILVQ 660
ESQQFKHNFL LLFMKLRWFL KRWRQGKVLP SEEDDFLEVN SMKELYLLME EEEMNAQHSD 720
NKACTGESWT QNTPNECIKT LADMKVTLKE LCWLLQDERR GLTELQQQFA KAKATWETER 780
AELKGHASQM ELKAGKGASE RPGPDWKAAL QREREEQQHL LAESYSAVME LTRQLQLSER 840
HWSQEKLQLV ERLQGEKQQV EQQVKELQNR LSQLQKAAEP WVLKHSDMEK QDNSWKEARS 900
EKTHDKEGVS EAELGGTGLK RTKSVSSMSE FESLLDCSPY LAGGDARNKK LPNGPAFAFV 960
STEPVEPEKD AKEKAGLSTR DCSHIGSLAC QEPAGRQMQR SYTAPDKTGI RVYYSPPVAR 1020
RLGVPVVHDK EGKILIEPGF LFTTAKPKES AEADGLAESS YSRWLCNFSR QRLDGGSGAS 1080
TSGSGPAFPA LHDFEMSGNM SDDMKEITNC VRQAMRSGSL ERKVKNTSSQ TVGVATVGTQ 1140
TIRTVSVGLQ TDPPRSSLHS KSWSPRSSSL VSVRSKQISS SLDKVHSRIE RPCCSPKYGS 1200
PKLQRRSVSK LDSTKDRSLW NLHQGKQNGS AWARSTTTRD SPVLRNINDG LSSLFSVVEH 1260
SGSTESVWKL GMSEARTKPE PPKYGIVQEF FRNVCGRAPS PTTAAGEESC KKPEPLSPAS 1320
YHQPEGVSRI LNKKAAKAGG SEEVRPTMLS QVGKDGILRD GDGSLILPSE DAVCDCSAQS 1380
LASCFIRPSR NTIRHSPSKC RLHPSESGWG GEERAAPQ 1419
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0964--Secreted
Interpro

IPR027882--DUF4482
IPR027881--SOGA
PROSITE
Pfam

PF11365--DUF3166
PF14818--DUF4482
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0008286--P:insulin receptor signaling pathway
GO:0045721--P:negative regulation of gluconeogenesis
GO:0010506--P:regulation of autophagy