dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0050272 | ||||||||
| Uniprot Accession | E0CYC6; NAT8B_MOUSE; | ||||||||
| Genbank Protein ID | |||||||||
| Genbank Nucleotide ID | |||||||||
| Protein Name | N-acetyltransferase 8B | ||||||||
| Protein Synonyms/Alias | Acetyltransferase 1;ATase1;Camello-like protein 2; | ||||||||
| Gene Name | Nat8b | ||||||||
| Gene Synonyms/Alias | Cml2; | ||||||||
| Organism | Mus musculus(Mouse) | ||||||||
| NCBI Taxa ID | 10090 | ||||||||
| Functional Description (View all) |
May have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6-acetylation of various proteins. Thereby, may regulate apoptosis through the acetylation and the regulation of the expression of PROM1. May also regulate amyloid beta-peptide secretion through acetylation of BACE1 and the regulation of its expression in neurons (By similarity). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MPRFEAQKSS MVPYHIRQYQ DSDHKRVVDV FTTGAEEYIP STFRHVLRLP RTFLLLLGVP 60 LALVLVSGSW ILAVICIFFL LLLLRLLARQ PWKEYVAKCL QTYMVDITKS YLNVHGACFW 120 VAESGGQVVG IVAAQPVKDP PLGRKQLQLF RLSVSSQHRG QGIAKALTRT VLQFARDQSY 180 SDVVLETSTL QQGAMTLYLG MGFKKTGQYF KSMFWRLVDI CFIQLNYSFP SA 233 |
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| Keyword | KW-0012--Acyltransferase |
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| Interpro | |||||||||
| PROSITE | PS51186--GNAT |
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| Pfam | PF00583--Acetyltransf_1 |
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| Gene Ontology | GO:0005789--C:endoplasmic reticulum membrane |