dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050258
Uniprot Accession D9HP81; D9HP81_MOUSE;
Genbank Protein ID NP_001243311.1;
Genbank Nucleotide ID NM_001256382.1;
Protein Name Regulating synaptic membrane exocytosis 2
Protein Synonyms/Alias
Gene Name Rims2
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
1117PSLMTGRSAPPSPALPhosphoSitePlus;curated22135298; 21183079
1121TGRSAPPSPALSRSHPhosphoSitePlus;curated22135298; 21183079
Sequence
(Fasta)		MSAPLGPRGR PAPTPAASQP PPQPEMPDLS HLTEEERKII LAVMDRQKKE EEKEQSVLKK 60
LHQQFEMYKE QVKKMGEESQ QQQEQKGDAP TCGICHKTKF ADGCGHNCSY CQTKFCARCG 120
GRVSLRSNKV MWVCNLCRKQ QEILTKSGAW FYNSGSNTLQ QPDQKVPRGL RNEEAPQEKK 180
AKLHEQPQFQ GAPGDLSVPA VEKGRAHGLT RQDTIKNGSG VKHQIASDMP SDRKRSPSVS 240
RDQNRRYEQS EEREDYSQYV PSDGTMPRSP SDYADRRSQR EPQFYEEPGH LNYRDSNRRG 300
HRHSKEYIVD DEDVESRDEY ERQRREEEYQ ARYRSDPNLA RYPVKPQPYE EQMRIHAEVS 360
RARHERRHSD VSLANAELED SRISLLRMDR PSRQRSVSER RAAMENQRSY SMERTREAQG 420
QSSYPQRTSN HSPPTPRRSP IPLDRPDMRR ADSLRKQHHL DPSSAVRKTK REKMETMLRN 480
DSLSSDQSES VRPPPPRPHK SKKGGKMRQV SLSSSEEELA STPEYTSCDD VELESESVSE 540
KGDSQKGKRK TSEQGVLSDS NTRSERQKKR MYYGGHSLEE DLEWSEPQIK DSGVDTCSST 600
TLNEEHSHSD KHPVTWQPSK DGDRLIGRIL LNKRLKDGSV PRDSGAMLGL KVVGGKMTES 660
GRLCAFITKV KKGSLADTVG HLRPGDEVLE WNGRLLQGAT FEEVYNIILE SKPEPQVELV 720
VSRPIGDIPR IPDSTHAQLE SSSSSFESQK MDRPSISVTS PMSPGMLRDV PQFLSGQLSI 780
KLWFDKVGHQ LIVTILGAKD LPSREDGRPR NPYVKIYFLP DRSDKNKRRT KTVKKTLEPK 840
WNQTFIYSPV HRREFRERML EITLWDQARV REEESEFLGE ILIELETALL DDEPHWYKLQ 900
THDVSSLPLP RPSPYLPRRQ LHGESPTRRL QRSKRISDSE VSDYDCEDGV GVVSDYRHNG 960
RDLQSSTLSV PEQVMSSNHC SPSGSPHRVD VIGRTRSWSP SAPPPQRNVE QGHRGTRATG 1020
HYNTISRMDR HRVMDDHYSS DRDSHFLTLP RSRHSQTIDH HHRDGRDCEA ADRQPYHRSR 1080
STEQRPLLER TTTRSRSSER PDTNLMRSMP SLMTGRSAPP SPALSRSHPR TGSVQTSPSS 1140
TPGTGRRGRQ LPQLPPKGTL ERSAMDIEER NRQMKLNKYK QVAGSDPRLE QDYHSKYRSG 1200
WDPHRGADTV STKSSDSDVS DVSAVSRTSS ASRFSSTSYM SVQSERPRGN RKISVFTSKM 1260
QNRQMGVSGK NLTKSTSISG DMCSLEKNDG SQSDTAVGAL GTSGKKRRSS IGAKMVAIVG 1320
LSRKSRSASQ LSQTEGGGKK LRSTVQRSTE TGLAVEMRNW MTRQASREST DGSMNSYSSE 1380
GNLIFPGVRL ASDSQFSDFL DGLGPAQLVG RQTLATPAMG DIQVGMMDKK GQLEVEIIRA 1440
RGLVVKPGSK TLPAPYVKVY LLDNGVCIAK KKTKVARKTL EPLYQQLLSF EESPQGRVLQ 1500
IIVWGDYGRM DHKSFMGVAQ ILLDELELSN MVIGWFKLFP PSSLVDPTLA PLTRRASQSS 1560
LESSTGPSYS RS 1573
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000008--C2_dom
IPR001478--PDZ
IPR010911--Rab_BD
IPR030631--RIM2
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50004--C2
PS50106--PDZ
PS50916--RABBD
PS50178--ZF_FYVE
Pfam

PF00168--C2
PF02318--FYVE_2
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005622--C:intracellular
GO:0048786--C:presynaptic active zone
GO:0044325--F:ion channel binding
GO:0046872--F:metal ion binding
GO:0017156--P:calcium ion-dependent exocytosis
GO:0048791--P:calcium ion-dependent exocytosis of neurotransmitter
GO:0019933--P:cAMP-mediated signaling
GO:0030073--P:insulin secretion
GO:0006886--P:intracellular protein transport
GO:0007269--P:neurotransmitter secretion
GO:1903861--P:positive regulation of dendrite extension
GO:0017157--P:regulation of exocytosis
GO:0042391--P:regulation of membrane potential