dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0050252
Uniprot Accession D6VTK4; STE2_YEAST; P06842; Q70D63; Q70D65; Q70D69; Q70D73; Q70D74;
Genbank Protein ID NP_116627.2;
Genbank Nucleotide ID NM_001179940.2;
Protein Name Pheromone alpha factor receptor
Protein Synonyms/Alias
Gene Name STE2
Gene Synonyms/Alias YFL026W;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c)(Baker's yeast)
NCBI Taxa ID 559292
Functional Description
(View all)		 Receptor for the peptide pheromone alpha factor, the mating factor of yeast.
Phosphorylation Sites
 dbPAF PTMs: 30 (View all)
PositionPeptidesSourceReferences ( PMIDs )
192AVKGMIVTYNDVSATcurated26040289
193VKGMIVTYNDVSATQcurated26040289
197IVTYNDVSATQDKYFcurated26040289
199TYNDVSATQDKYFNAcurated26040289
310SKTNTITSDFTTSTDdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19060867; 19366988; 22817900
313NTITSDFTTSTDRFYPhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.017330950; 19060867; 19366988
315ITSDFTTSTDRFYPGPhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated19779198; 17330950; 19060867; 19366988; 26040289; 22817900
325RFYPGTLSSFQTDSIPhosphoGRID 2.0;PhosphoPep 2.0;curated19684113; 19060867; 22817900
326FYPGTLSSFQTDSINPhosphoPep 2.0;curated19060867; 25704821; 19823750
329GTLSSFQTDSINNDAdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19779198; 19060867; 19366988;
331LSSFQTDSINNDAKSdbPTM 3.0;PhosphoGRID 2.0;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19828733; 19684113; 19779198;
338SINNDAKSSLRSRLYPhosphoGRID 2.0;PhosphoPep 2.0;curated19828733; 19779198; 19060867; 22817900; 25882841
339INNDAKSSLRSRLYDPhosphoGRID 2.0;PhosphoPep 2.0;curated19828733; 19779198; 19060867; 22817900
342DAKSSLRSRLYDLYPPhosphoGRID 2.019828733
355YPRRKETTSDKHSERcurated19823750
356PRRKETTSDKHSERTPhosphoGRID 2.019828733
360ETTSDKHSERTFVSEdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19828733; 19366988; 25704821;
363SDKHSERTFVSETADdbPTM 3.0;PhosphoGRID 2.0;SysPTM 2.0;UniProt;curated17330950; 16381945; 23193290; 19366988; 26040289; 25704821;
366HSERTFVSETADDIEdbPTM 3.0;PhosphoGRID 2.0;PHOSIDA;PhosphoPep 2.0;SysPTM 2.0;UniProt;curated15665377; 17287358; 17330950; 16381945; 23193290; 19779198;
368ERTFVSETADDIEKNPhosphoGRID 2.0;curated19823750; 19795423
Sequence
(Fasta)		MSDAAPSLSN LFYDPTYNPG QSTINYTSIY GNGSTITFDE LQGLVNSTVT QAIMFGVRCG 60
AAALTLIVMW MTSRSRKTPI FIINQVSLFL IILHSALYFK YLLSNYSSVT YALTGFPQFI 120
SRGDVHVYGA TNIIQVLLVA SIETSLVFQI KVIFTGDNFK RIGLMLTSIS FTLGIATVTM 180
YFVSAVKGMI VTYNDVSATQ DKYFNASTIL LASSINFMSF VLVVKLILAI RSRRFLGLKQ 240
FDSFHILLIM SCQSLLVPSI IFILAYSLKP NQGTDVLTTV ATLLAVLSLP LSSMWATAAN 300
NASKTNTITS DFTTSTDRFY PGTLSSFQTD SINNDAKSSL RSRLYDLYPR RKETTSDKHS 360
ERTFVSETAD DIEKNQFYQL PTPTSSKNTR IGPFADASYK EGEVEPVDMY TPDTAADEEA 420
RKFWTEDNNN L 432
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0297--G-protein coupled receptor
KW-0325--Glycoprotein
KW-0472--Membrane
KW-0589--Pheromone response
KW-0597--Phosphoprotein
KW-0675--Receptor
KW-1185--Reference proteome
KW-0807--Transducer
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR000366--GPCR_STE2
IPR027458--STE2_TM1-TM2
PROSITE
Pfam

PF02116--STE2
Gene Ontology

GO:0038038--C:G-protein coupled receptor homodimeric complex
GO:0005887--C:integral component of plasma membrane
GO:0004934--F:mating-type alpha-factor pheromone receptor activity
GO:0005550--F:pheromone binding
GO:0030031--P:cell projection assembly
GO:0000755--P:cytogamy
GO:0000750--P:pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0031139--P:positive regulation of conjugation with cellular fusion
GO:0051260--P:protein homooligomerization
GO:0035624--P:receptor transactivation