dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0048291
Uniprot Accession D3Z7R4; D3Z7R4_MOUSE;
Genbank Protein ID
Genbank Nucleotide ID
Protein Name Synaptotagmin-1
Protein Synonyms/Alias
Gene Name Syt1
Gene Synonyms/Alias
Organism Mus musculus(Mouse)
NCBI Taxa ID 10090
Functional Description
(View all)
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
122DQDDDAETGLTDGEEcurated25521595
125DDAETGLTDGEEKEEcurated25521595
Sequence
(Fasta)
MVSASRPEAL AAPVTTVATL VPHNATEPAS PGEGKEDAFS KLKQKFMNEL HKIPLPPWAL 60
IAIAIVAVLL VVTCCFCVCK KCLFKKKNKK KGKEKGGKNA INMKDVKDLG KTMKDQDDDA 120
ETGLTDGEEK EEPKEEEKLG KLQYSLDYDF QNNQLLVGII QAAELPALDM GGTSDPYVKV 180
FLLPDKKKKF ETKVHRKTLN PVFNEQFTFK VPYSELGGKT LVMAVYDFDR FSKHDI 237
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000008--C2_dom
IPR001565--Synaptotagmin
IPR015428--Synaptotagmin1

PROSITE

PS50004--C2

Pfam

PF00168--C2

Gene Ontology

GO:0005737--C:cytoplasm
GO:0031045--C:dense core granule
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0043005--C:neuron projection
GO:0042734--C:presynaptic membrane
GO:0030141--C:secretory granule
GO:0008021--C:synaptic vesicle
GO:0030672--C:synaptic vesicle membrane
GO:0005509--F:calcium ion binding
GO:0005544--F:calcium-dependent phospholipid binding
GO:0030276--F:clathrin binding
GO:0050750--F:low-density lipoprotein particle receptor binding
GO:0005546--F:phosphatidylinositol-4,5-bisphosphate binding
GO:0019905--F:syntaxin binding
GO:0007269--P:neurotransmitter secretion
GO:1903861--P:positive regulation of dendrite extension
GO:0017158--P:regulation of calcium ion-dependent exocytosis
GO:0048488--P:synaptic vesicle endocytosis
GO:0016079--P:synaptic vesicle exocytosis