dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0045916
Uniprot Accession A0ZWU1; EAF1_SCHPO;
Genbank Protein ID XP_001713171.1;
Genbank Nucleotide ID XM_001713119.2;
Protein Name Ell1-associated factor 1
Protein Synonyms/Alias
Gene Name eaf1
Gene Synonyms/Alias SPCC1223.10c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Activates transcription elongation by RNA polymerase II and pyrophosphorolysis as a complex with ell1. Acts as a transcriptional transactivator of ell1 elongation activities.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
247AEGISSASEDED---dbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MNSLQKGSYK VIPGSSFSKN SNGLLSIKYN FIPESVDPSR RGVLEKAQEA YRLRLPSTFD 60
DDRPHIFEGS CQRARNVDCV LIFNAKTKTF TLEHIDEIAR LNALRNPKVS KTVPSNAITQ 120
SDNSQISESK STSQSAVTTN STRRKEKELE ASKDGKIKPS SSNTRYPAIS SKGPITTDTN 180
DEPDMEVMEL DDFAKELELG FDQEFNSIDD PSTVSQTASK PISLRGLSSQ ERDYASSAQA 240
EGISSASEDE D 252
Keyword

KW-0010--Activator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR027093--EAF_fam
IPR019194--Tscrpt_elong_fac_Eaf_N

PROSITE
Pfam

PF09816--EAF

Gene Ontology

GO:0032783--C:ELL-EAF complex
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006368--P:transcription elongation from RNA polymerase II promoter