dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0044143
Uniprot Accession Q9Y823; HOSM_SCHPO;
Genbank Protein ID NP_596458.1;
Genbank Nucleotide ID NM_001022377.2;
Protein Name Homocitrate synthase, mitochondrial
Protein Synonyms/Alias
Gene Name lys4
Gene Synonyms/Alias SPBC1105.02c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
202ADTVGCATPRQVYDLdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
353VHVGSRLTGWNAIKScurated22817900
360TGWNAIKSRAEQLNLcurated22817900
407REYHADLSDADRITKcurated22817900
Sequence
(Fasta)		MSVSEANGTE TIKPPMNGNP YGPNPSDFLS RVNNFSIIES TLREGEQFAN AFFDTEKKIQ 60
IAKALDNFGV DYIELTSPVA SEQSRQDCEA ICKLGLKCKI LTHIRCHMDD ARVAVETGVD 120
GVDVVIGTSQ YLRKYSHGKD MTYIIDSATE VINFVKSKGI EVRFSSEDSF RSDLVDLLSL 180
YKAVDKIGVN RVGIADTVGC ATPRQVYDLI RTLRGVVSCD IECHFHNDTG MAIANAYCAL 240
EAGATHIDTS ILGIGERNGI TPLGALLARM YVTDREYITH KYKLNQLREL ENLVADAVEV 300
QIPFNNYITG MCAFTHKAGI HAKAILANPS TYEILKPEDF GMSRYVHVGS RLTGWNAIKS 360
RAEQLNLHLT DAQAKELTVR IKKLADVRTL AMDDVDRVLR EYHADLSDAD RITKEASA 419
Keyword

KW-0002--3D-structure
KW-0028--Amino-acid biosynthesis
KW-0181--Complete proteome
KW-0457--Lysine biosynthesis
KW-0496--Mitochondrion
KW-1185--Reference proteome
KW-0808--Transferase
KW-0809--Transit peptide
Interpro

IPR002034--AIPM/Hcit_synth_CS
IPR013785--Aldolase_TIM
IPR011872--Homocitrate_synth_fun/arc
IPR000891--PYR_CT
PROSITE

PS00815--AIPM_HOMOCIT_SYNTH_1
PS00816--AIPM_HOMOCIT_SYNTH_2
PS50991--PYR_CT
Pfam

PF00682--HMGL-like
Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005634--C:nucleus
GO:0004410--F:homocitrate synthase activity
GO:0009085--P:lysine biosynthetic process
GO:0019878--P:lysine biosynthetic process via aminoadipic acid