dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0044126
Uniprot Accession Q9Y7R5; INS1_SCHPO;
Genbank Protein ID NP_587813.1;
Genbank Nucleotide ID NM_001022806.2;
Protein Name INSIG family protein
Protein Synonyms/Alias
Gene Name ins1
Gene Synonyms/Alias SPCC306.05c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
28RAVKKSLSVLSLDNMdbPTM 3.0;UniProt18257517; 16381945; 23193290
31KKSLSVLSLDNMKSTdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)		MSRKEIYEPR PRYPDGYNGN RAVKKSLSVL SLDNMKSTLS GLFAPLKLDE EQAEDDESLS 60
SYEDYASRQI DDDLKKQRKK GITFIDYSSL ITFFCKLCVI FGLGFVFTYL AEQIVQDAKL 120
PLLTVNLKSW KFEPPWPAIF GFVAVILGLS YRRMDTKYPL GAAPLRPSQS SKWQWISRYL 180
AAFATLLLSM KKLLFISNSH SIVALVASSA SIWYIFDRSR NGIILSTITS VLGSILYYNL 240
VDTSKIELNG VEFPEIQFRL WIPMILFSAS TIVGNAGRLL F 282
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR025929--INSIG_fam
PROSITE
Pfam

PF07281--INSIG
Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0071458--C:integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0032936--C:SREBP-SCAP complex
GO:0071456--P:cellular response to hypoxia
GO:0035437--P:maintenance of protein localization in endoplasmic reticulum
GO:0010895--P:negative regulation of ergosterol biosynthetic process
GO:2001216--P:negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0001934--P:positive regulation of protein phosphorylation
GO:0035103--P:sterol regulatory element binding protein cleavage