dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0044119
Uniprot Accession Q9Y7N0; BDF1_SCHPO; Q9UUN2;
Genbank Protein ID NP_588301.2;
Genbank Nucleotide ID NM_001023291.2;
Protein Name SWR1 complex bromodomain subunit bdf1
Protein Synonyms/Alias
Gene Name bdf1
Gene Synonyms/Alias brf1;SPCC1450.02;SPCC191.13;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.
Phosphorylation Sites
 dbPAF PTMs: 9
PositionPeptidesSourceReferences ( PMIDs )
220PPRTRRNSSVSSTSAcurated22817900
221PRTRRNSSVSSTSASdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
223TRRNSSVSSTSASVAdbPTM 3.0;UniProt18257517; 16381945; 23193290
224RRNSSVSSTSASVAAdbPTM 3.0;UniProt18257517; 16381945; 23193290
225RNSSVSSTSASVAASdbPTM 3.0;UniProt18257517; 16381945; 23193290
226NSSVSSTSASVAASTdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
239STAPKAASPAVLPEGdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
408AAVDKQISMLQDTLEcurated22817900
511ADSSEPASPVLMPTKdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
Sequence
(Fasta)		MSSESRENEV KAETKDEIAN DGSPQLNGDN NIQSSDGHND ENEESLSRKR DSSGATVGDL 60
KQEEKESMPK KEPEPTVKKI RGSGMPPPQQ KYCLAIVRQL KRTKNSAPFK VPVDPIKQNI 120
PDYPTIVKNP MDLGTIEKKL TSYEYSVPQE FIDDMNLMFS NCFLYNGTES PVGSMGKALQ 180
EVFERQLKQL PDAEQPAAAP VKKSKQKSAS TAPPRTRRNS SVSSTSASVA ASTAPKAASP 240
AVLPEGKPRR RKNNSQMRFC STVLKELYKR QYESFAFPFY QPVDPVACDC PDYFDVIKEP 300
MDLSTIQSKL NKNEYSTLEE FESDILLMFN NCFTYNPPGT PVHVMGRQLE NVFKEKWEAR 360
PKFDDATLVK QQEAETDALF DNGEEEEALM SEEEINGAKF AAVDKQISML QDTLEAMKAK 420
KMNRMRKPRR RDLTKEYGPI TYAMQNELAE RCNYLSAEQL SNVAEILREE MPWLRDTDEI 480
EIDVGNMKPE VFHRIYRYVC KPDADSSEPA SPVLMPTKPE KKKGRVLSET EQAEKIRRLQ 540
QQLDRFAGKT SPTSPESNNA ANVSDSESDN ESESSESA 579
Keyword

KW-0010--Activator
KW-0103--Bromodomain
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR027353--NET_dom
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51525--NET
Pfam

PF17035--BET
PF00439--Bromodomain
Gene Ontology

GO:0005634--C:nucleus
GO:0000812--C:Swr1 complex
GO:0016568--P:chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated