| Tag |
Content |
| dbPAF ID |
dbPAF-0044111 |
| Uniprot Accession |
Q9Y7K2; TOR2_SCHPO; O94507;
|
| Genbank Protein ID |
NP_595359.2;
|
| Genbank Nucleotide ID |
NM_001021266.3;
|
| Protein Name |
Phosphatidylinositol 3-kinase tor2 |
| Protein Synonyms/Alias |
|
| Gene Name |
tor2 |
| Gene Synonyms/Alias |
SPBC216.07c;SPBC646.01c; |
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Phosphatidylinositol 3-kinase homolog required for G1 progression.Functional Description
Phosphatidylinositol 3-kinase homolog required for G1 progression. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MKEFPGLKSR NEEIRNKAAN DLYEYVIAYS RELSGEALVQ FNNDVNKYVY TLIHSTDPLD 60
RLAGVTAINR LIDYEGEDTT RITRFANYLR IILPGTDQKA TVLAAKALGR LAVPGGALTS 120
EFVNFEVKRA LEWLQGERNE NRRYAAVLIL KELAKNTSTL IYAHIDSIFE LLWHGLRDPK 180
VTIRIASADA LSEFLKIVRQ RDSSIRLQWY TSILNEAQRG VAQGSSDYIH GSLLVYRQLF 240
LKAGMFMHER YREVSDIILQ FRDHKDLLIR KTVTELIATL AAYNPDEFVS NYLHVCMLHL 300
LNLLKKENVK MLAFATIGKV AVAITNSIIP YLDPICDSIK ESLKIHIRNK SASDAAIFQC 360
ISLLSIALGQ AFSNYAYDLF DLIFASGLSE ASYRALSDLA HNIPPLLPVI QERLLDMLSK 420
ILSGRPFIPP GCPPQYVARS LKSSKSASLK TGFFPNDVYI LALKVLGNFD FSGYILNEFV 480
KDCVVVYLEN NDPEVRKTAS ITCSQLFARD PILSQTSDHA IQVVAEVLEK LLTVGICDTV 540
PDIRLTVLNS LDSRFNKHLA QADKIRLLFI AINDENFAVR ESALRIIGRL NVYNPAYVMP 600
YLRKIMLKTL TILDYSTIIR TKEENAKLLC LLIAAAPRLI ESHVEPILQI LLPKAKDSSS 660
IVAASIVNSL GEICQISGEV IVPFIKDLMP LIIEALQDQS SPIRRAAALK ALGNLSSSTG 720
YVIDPYIEFP SLLDILIGIT KTEQDITIRR ETIKLIGTLG ALDPNRHRVL EKGTEKVVPE 780
QKNIPPDISL LMSGIGPSSD EYYPTVVITA LMSILKDPSL TIHHTAVIQA VMYIFKTMGL 840
RCAPFLSQII PEFIAVMRTC PTNILEFYFQ QLSILVLIVR QHIRSFLPDL FKLIKDFWNP 900
HSNLQFTILS LIESLARAMQ GEFKPYLPSL LVMMLQIFDS DVSVDSVSTK KVLHAFIVFG 960
DTLADYFHML LDPILRLYER NDVSIGIKES IMITIGRLSM VINLSEYASR IIHPVMRMLS 1020
CNNASLIRVS MDTVCALIYQ LNVDFAIFIP MIDKCLKMNG VTHETYSILV EQFLQEQPLP 1080
IKLNPYEKYD KPKLDVVASA ADITSKKLPV NQEILRNAWE ASQRSTKDDW QEWIRRLGVA 1140
LLRESPSHAL RACAALAAAY QPLARDLFNA SFVSCWSELY DHFQEELVKS IEIALTSPHI 1200
SPEIIQILLN LAEFMEHDDK PLPIDIRTLG AYAAKCHAFA KALHYKELEF IEEELVTKPS 1260
VDTIEALISI NNQLQQPDAA IGILKHAQQH DKMNLKETWY EKLQRWEDAL SAYEKREAAG 1320
AGNFEITMGK LRCLHALGEW DRLSQLAQEN WIHAGHDARR YIAPLSVAAA WGLGQWEQMD 1380
EYISVMKSES PDKAFFNAIV ALHRSQFEEA ASYITRARDL LDTELTALVG ESYNRAYSVA 1440
VRVQMLSELE EIITYKKAED KPEVREMIKK TWVRRLKGCQ RNVDVWQRML RIRSLVISPR 1500
DNMEMWIKFA NLCRKSGRIS LAKKSLNLLL EDDENLDNSL VLKKTHPSIV YANLKFLWAV 1560
DDKRKALNSM QEFTSQLISD INVDPALFVQ STSVNTQKSQ EEIQYYFHLL ARCYHKQGQW 1620
QQEIENNWSE GSFDGVLQSY MYATQFDSKW YKAWHSWALA NFEAVKFLEQ SEEQIPSAAY 1680
EQYIIPAVKG FFKSIALSKG NLQDTLRLLN LWFKFGNNSN VINTLNVGIS TVNIDIWLDV 1740
IPQLIARIHA SSLSVRKSVH QLLSDVGRAH PQALVYPLTV AAKSQSSARQ NAALAIMDSL 1800
KTHSPRLVEQ ARLVSHELIR AAILWHEQWH EGLEEASRLY FGDHNIEGMF AVLRPLHEML 1860
ERGPETLREI SFQQAFGRDL VEARDCCIRF EQTGDISDLN QAWDLYYQVF KKIRKQLPQL 1920
TTLDLQYVSP KLLHVHDLEL AVPGTYVSGK PVIRIVKFYP TFNVITSKQR PRRLSIKGSD 1980
GKDYQYVLKG HEDIRQDERV MQLFGLCNNL LLADPETFKR LLSIQRYPVI PLSPDSGLLG 2040
WVLDSDTLHV LIRDYRESRK ILLNIEHRLI IQMAPDYDRL TLLQKVEVFE YALLSTTGQD 2100
LYRVLWLKSR SSEAWLNRRT NYSRTLAVMS MVGYILGLGD RHPSNLMLDR YTGNIIHIDF 2160
GDCFEVAMHR EKFPEKIPFR LTRMLVNAME VSGIEGTFRI TCEHVMRVLR TNKESVMAVL 2220
EAFVYDPLIN WRLAPAYSPS IDEKQSNEPN TLLGETIDGL HRKRLNEEGI TLEERQKPEI 2280
LNQRAITVLN RVSNKLTGRD FKPQQQLDVP SQVEKLILQA TSIENLCLCY IGWCSFW
2338Fasta Sequence
>Q9Y7K2|tor2|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MKEFPGLKSRNEEIRNKAANDLYEYVIAYSRELSGEALVQFNNDVNKYVYTLIHSTDPLDRLAGVTAINRLIDYEGEDTTRITRFANYLRIILPGTDQKATVLAAKALGRLAVPGGALTSEFVNFEVKRALEWLQGERNENRRYAAVLILKELAKNTSTLIYAHIDSIFELLWHGLRDPKVTIRIASADALSEFLKIVRQRDSSIRLQWYTSILNEAQRGVAQGSSDYIHGSLLVYRQLFLKAGMFMHERYREVSDIILQFRDHKDLLIRKTVTELIATLAAYNPDEFVSNYLHVCMLHLLNLLKKENVKMLAFATIGKVAVAITNSIIPYLDPICDSIKESLKIHIRNKSASDAAIFQCISLLSIALGQAFSNYAYDLFDLIFASGLSEASYRALSDLAHNIPPLLPVIQERLLDMLSKILSGRPFIPPGCPPQYVARSLKSSKSASLKTGFFPNDVYILALKVLGNFDFSGYILNEFVKDCVVVYLENNDPEVRKTASITCSQLFARDPILSQTSDHAIQVVAEVLEKLLTVGICDTVPDIRLTVLNSLDSRFNKHLAQADKIRLLFIAINDENFAVRESALRIIGRLNVYNPAYVMPYLRKIMLKTLTILDYSTIIRTKEENAKLLCLLIAAAPRLIESHVEPILQILLPKAKDSSSIVAASIVNSLGEICQISGEVIVPFIKDLMPLIIEALQDQSSPIRRAAALKALGNLSSSTGYVIDPYIEFPSLLDILIGITKTEQDITIRRETIKLIGTLGALDPNRHRVLEKGTEKVVPEQKNIPPDISLLMSGIGPSSDEYYPTVVITALMSILKDPSLTIHHTAVIQAVMYIFKTMGLRCAPFLSQIIPEFIAVMRTCPTNILEFYFQQLSILVLIVRQHIRSFLPDLFKLIKDFWNPHSNLQFTILSLIESLARAMQGEFKPYLPSLLVMMLQIFDSDVSVDSVSTKKVLHAFIVFGDTLADYFHMLLDPILRLYERNDVSIGIKESIMITIGRLSMVINLSEYASRIIHPVMRMLSCNNASLIRVSMDTVCALIYQLNVDFAIFIPMIDKCLKMNGVTHETYSILVEQFLQEQPLPIKLNPYEKYDKPKLDVVASAADITSKKLPVNQEILRNAWEASQRSTKDDWQEWIRRLGVALLRESPSHALRACAALAAAYQPLARDLFNASFVSCWSELYDHFQEELVKSIEIALTSPHISPEIIQILLNLAEFMEHDDKPLPIDIRTLGAYAAKCHAFAKALHYKELEFIEEELVTKPSVDTIEALISINNQLQQPDAAIGILKHAQQHDKMNLKETWYEKLQRWEDALSAYEKREAAGAGNFEITMGKLRCLHALGEWDRLSQLAQENWIHAGHDARRYIAPLSVAAAWGLGQWEQMDEYISVMKSESPDKAFFNAIVALHRSQFEEAASYITRARDLLDTELTALVGESYNRAYSVAVRVQMLSELEEIITYKKAEDKPEVREMIKKTWVRRLKGCQRNVDVWQRMLRIRSLVISPRDNMEMWIKFANLCRKSGRISLAKKSLNLLLEDDENLDNSLVLKKTHPSIVYANLKFLWAVDDKRKALNSMQEFTSQLISDINVDPALFVQSTSVNTQKSQEEIQYYFHLLARCYHKQGQWQQEIENNWSEGSFDGVLQSYMYATQFDSKWYKAWHSWALANFEAVKFLEQSEEQIPSAAYEQYIIPAVKGFFKSIALSKGNLQDTLRLLNLWFKFGNNSNVINTLNVGISTVNIDIWLDVIPQLIARIHASSLSVRKSVHQLLSDVGRAHPQALVYPLTVAAKSQSSARQNAALAIMDSLKTHSPRLVEQARLVSHELIRAAILWHEQWHEGLEEASRLYFGDHNIEGMFAVLRPLHEMLERGPETLREISFQQAFGRDLVEARDCCIRFEQTGDISDLNQAWDLYYQVFKKIRKQLPQLTTLDLQYVSPKLLHVHDLELAVPGTYVSGKPVIRIVKFYPTFNVITSKQRPRRLSIKGSDGKDYQYVLKGHEDIRQDERVMQLFGLCNNLLLADPETFKRLLSIQRYPVIPLSPDSGLLGWVLDSDTLHVLIRDYRESRKILLNIEHRLIIQMAPDYDRLTLLQKVEVFEYALLSTTGQDLYRVLWLKSRSSEAWLNRRTNYSRTLAVMSMVGYILGLGDRHPSNLMLDRYTGNIIHIDFGDCFEVAMHREKFPEKIPFRLTRMLVNAMEVSGIEGTFRITCEHVMRVLRTNKESVMAVLEAFVYDPLINWRLAPAYSPSIDEKQSNEPNTLLGETIDGLHRKRLNEEGITLEERQKPEILNQRAITVLNRVSNKLTGRDFKPQQQLDVPSQVEKLILQATSIENLCLCYIGWCSFW
|
| Keyword |
KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
|
| Interpro |
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR024585--DUF3385_TOR
IPR003152--FATC_dom
IPR000357--HEAT
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000403--PI3/4_kinase_cat_dom
IPR018936--PI3/4_kinase_CS
IPR003151--PIK-rel_kinase_FAT
IPR014009--PIK_FAT
IPR009076--Rapamycin-bd_dom
IPR026683--TOR
|
| PROSITE |
PS51189--FAT
PS51190--FATC
PS50077--HEAT_REPEAT
PS00915--PI3_4_KINASE_1
PS00916--PI3_4_KINASE_2
PS50290--PI3_4_KINASE_3
|
| Pfam |
PF11865--DUF3385
PF02259--FAT
PF02260--FATC
PF02985--HEAT
PF00454--PI3_PI4_kinase
PF08771--Rapamycin_bind
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0034064--C:Tor2-Mei2-Ste11 complex
GO:0031931--C:TORC1 complex
GO:0016303--F:1-phosphatidylinositol-3-kinase activity
GO:0005524--F:ATP binding
GO:0008144--F:drug binding
GO:0016301--F:kinase activity
GO:0000724--P:double-strand break repair via homologous recombination
GO:0030996--P:mitotic cell cycle arrest in response to nitrogen starvation
GO:0010507--P:negative regulation of autophagy
GO:0010503--P:negative regulation of cell cycle arrest in response to nitrogen starvation
GO:0010515--P:negative regulation of induction of conjugation with cellular fusion
GO:0007165--P:signal transduction
GO:0031929--P:TOR signaling
|
