| Tag |
Content |
| dbPAF ID |
dbPAF-0044109 |
| Uniprot Accession |
Q9Y7I8; ZUO1_SCHPO; O14347;
|
| Genbank Protein ID |
NP_596284.2;
|
| Genbank Nucleotide ID |
NM_001022205.3;
|
| Protein Name |
Zuotin |
| Protein Synonyms/Alias |
DnaJ-related protein zuo1;J protein zuo1;Ribosome-associated complex subunit zuo1; |
| Gene Name |
zuo1 |
| Gene Synonyms/Alias |
SPBC1778.01c;SPBC30D10.01; |
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state. RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain (By similarity).Functional Description
Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state. RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain (By similarity). |
Phosphorylation Sites
|
dbPAF PTMs: 6 |
Sequence
(Fasta) | MSAGDSIQLF PPTTKQAIEA SFVPHGKISP LIKRAVEPVG PLFLAHARRQ RHGRTFSEDE 60
RLEVKNKVQE EVKEESEDEE EDPAMLRADP KEWKQQDHYA VLGLSKYRYK ADTEQIKKAH 120
LKKVLKHHPD KKAASGNIND DSFFKCIQKA YEILSDPVRR RQFDSVDENA DVEPPESTTK 180
ETFFELWTPV FESEARFSKK QPVPSLGTIE STRAEVDNFY NFWYNFDSWR SFEYLDKDIP 240
DDGESRDNKR FQEKKNRSER QKNKARDNAR LRNLVDTALA SDPRIKLFKE QEKAAKAARK 300
WEREAGAREA AAAAQKKKEE EERRAAEEAA AKASAAAANK KAKEDKKKAQ KRDKKVVKNA 360
LKDFNYFSAT DVPSAEHVDS VLKDVDVIMS KLGEGELGQL AADINAEKAA GAASVQAVFD 420
KFAKMFIERG SMSSADVVFF AQ
443Fasta Sequence
>Q9Y7I8|zuo1|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MSAGDSIQLFPPTTKQAIEASFVPHGKISPLIKRAVEPVGPLFLAHARRQRHGRTFSEDERLEVKNKVQEEVKEESEDEEEDPAMLRADPKEWKQQDHYAVLGLSKYRYKADTEQIKKAHLKKVLKHHPDKKAASGNINDDSFFKCIQKAYEILSDPVRRRQFDSVDENADVEPPESTTKETFFELWTPVFESEARFSKKQPVPSLGTIESTRAEVDNFYNFWYNFDSWRSFEYLDKDIPDDGESRDNKRFQEKKNRSERQKNKARDNARLRNLVDTALASDPRIKLFKEQEKAAKAARKWEREAGAREAAAAAQKKKEEEERRAAEEAAAKASAAAANKKAKEDKKKAQKRDKKVVKNALKDFNYFSATDVPSAEHVDSVLKDVDVIMSKLGEGELGQLAADINAEKAAGAASVQAVFDKFAKMFIERGSMSSADVVFFAQ
|
| Keyword |
KW-0143--Chaperone
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0238--DNA-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
|
| Interpro |
IPR001623--DnaJ_domain
IPR018253--DnaJ_domain_CS
IPR032003--RAC_head
|
| PROSITE |
PS00636--DNAJ_1
PS50076--DNAJ_2
|
| Pfam |
PF00226--DnaJ
PF16717--RAC_head
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0003677--F:DNA binding
GO:0030544--F:Hsp70 protein binding
GO:0051082--F:unfolded protein binding
GO:0002182--P:cytoplasmic translational elongation
GO:0006457--P:protein folding
GO:0006450--P:regulation of translational fidelity
|
