dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0044107 |
| Uniprot Accession | Q9Y738; MIS12_SCHPO; |
| Genbank Protein ID | NP_595454.1; |
| Genbank Nucleotide ID | NM_001021364.2; |
| Protein Name | Centromere protein mis12 |
| Protein Synonyms/Alias | NMS complex subunit mis12; |
| Gene Name | mis12 |
| Gene Synonyms/Alias | SPBC409.04c; |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID | 284812 |
| Functional Description (View all) |
Acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. Required for correct segregation of chromosomes and for maintaining the inner centromere structure. |
| Phosphorylation Sites |
dbPAF PTMs: 3 |
| Sequence (Fasta) | MLVELLEFTP LSFIDDVINI TNQLLYKGVN GVDKAFSQTR FAKKAPQEIE EGLHKFEVLF 60 ESVVDRYYDG FEVYTLRNIF SYPPELKGYM RTFGKDVDYS ITTEQDAAMD QAIQEAAEKL 120 VVKMQLRRDL RMRLSRKREK KTEIEKHLER ISFLNKVPEN WQVTLPETTD FLLDQLGNLQ 180 HAVKRVVEAS PTVHSREVDE RITYLEKGYE RLSNPIDQQK DFWSHHLSKL ESTANTETAN 240 NIHKLLLSSE KDVGHTDEP |
| Keyword | KW-0131--Cell cycle |
| Interpro | IPR008685--Centromere_Mis12 |
| PROSITE | |
| Pfam | PF05859--Mis12 |
| Gene Ontology | GO:0034506--C:chromosome, centromeric core domain |