dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040926
Uniprot Accession Q9UUI5; SEC24_SCHPO; P78800;
Genbank Protein ID NP_594731.1;
Genbank Nucleotide ID NM_001020159.2;
Protein Name Protein transport protein sec24
Protein Synonyms/Alias
Gene Name sec24
Gene Synonyms/Alias SPAC22F8.08;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
126YVMARTPSSSPYPHDcurated22817900
Sequence
(Fasta)
MSQEDAFYGK GSYGASSGNS NIPPQGFQPV YPVAGQLDNT APYVGAVAEG TAEGIVSNGE 60
YAVGAMGAAP TNIIGSVDQQ PPVSHTSHKS RRQYPAEVFE LTNTLAASPA PPSLSEPSYV 120
MARTPSSSPY PHDRAEVGTK SLSAQFGGMS LGADGAAAMP TNELVSVDLY NQTPEISDLT 180
SPPPPINLPL SYSATGAATS NCPPKYVRST INCVPTTNSL LKKSKIPFAL VIRPYTSLVE 240
EDDPVPVVTD TIISRCRRCR MYINPFSIFI DNGHRYRCNS CGIVNEVPQS YDWDSFRNVQ 300
RDRWQRPELN YAVVDFIAPQ EYMVRAPQPL VYVFLIDISF VSISSGMVGT ASRAILESLD 360
RIPNKEGRAK VAFIGVDSAL HFFSVSPGAE EATQLVVSDL EEPFLPRNQD LLLNLRECRQ 420
GIENLLERFQ SMFATTRDSS NALGPGLKAA HRLIENIGGK ICCLISSLPN VGVGKLELRE 480
DPKLLGTNRE SSLLHPNDSF YKSFAVECST SQVSVDMFLF SSQYQDVATL SCLPRYTSGK 540
TQFYHRWNAS RSEDALKFAS ELTNYLSMEI ELEAVMRVRG SNGLRMSSFY GNFFNRSSDL 600
CAFPSFPRDQ SYVVEVVIED TITKPFVSFQ TAMLHTTCNG ERRIRVLTIS LPTTNSMTDL 660
YASADQVAIA QYLTVRASEK ALSSTLNEAR DSIISKLVEI LEVYKKNLAG QNTGAAIPLQ 720
ISTNLRLLPL LCLALTKHTG FRRSSHISSD LRSIALCYLS TLPTPLLMRY IYPTLYSLHD 780
MPIEAGTVTE QGVVLPSALN LTSALLQSFG LYLVDTHIHQ FLYIGKDAVP QLLIDAFGVN 840
SLADLKAGRF TMPVIDNPLN VRINAILGKL RSLDKGSTIM PSLYLVRGDG DPQLRSWFFS 900
HFVEDRSENS PSYLQFLQTL KEKVRD 927
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0479--Metal-binding
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0862--Zinc

Interpro

IPR029006--ADF-H/Gelsolin-like_dom
IPR007123--Gelsolin-like_dom
IPR006900--Sec23/24_helical_dom
IPR006896--Sec23/24_trunk_dom
IPR012990--Sec23_24_beta_S
IPR002035--VWF_A
IPR006895--Znf_Sec23_Sec24

PROSITE
Pfam

PF00626--Gelsolin
PF08033--Sec23_BS
PF04815--Sec23_helical
PF04811--Sec23_trunk
PF04810--zf-Sec23_Sec24

Gene Ontology

GO:0030127--C:COPII vesicle coat
GO:0005829--C:cytosol
GO:0070971--C:endoplasmic reticulum exit site
GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0008270--F:zinc ion binding
GO:0090110--P:cargo loading into COPII-coated vesicle
GO:0006886--P:intracellular protein transport