dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040924
Uniprot Accession Q9UUI3; SA145_SCHPO;
Genbank Protein ID NP_594733.1;
Genbank Nucleotide ID NM_001020161.2;
Protein Name Pre-mRNA-splicing factor sap145
Protein Synonyms/Alias Spliceosome-associated protein 145;
Gene Name sap145
Gene Synonyms/Alias SPAC22F8.10c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Involved in pre-mRNA splicing. May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity).
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
161YSDDEILSEGEEDALdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MYLLTRPKHC CLDFLLMAEI QTAQNPLKEL EKILERNNKQ KNKKSRNQVR REKKKLLREK 60
TNSGAKLAEK NSDDKDQLTE NNDNLYNDKK SNGNFYDTNK TDSVDGMVYT TIVDSVELDP 120
NDPLIEQFKD VFNRFKADGQ EKDFEDTDKG QIMYSDDEIL SEGEEDALQK QQEEKLSKKK 180
LRKLKRMTVA QLKMLSEKAD VVEWWDVSSL DPLFLTHLKA YPNTVPVPRH WNQKRDYLSG 240
QRGIERQLFE LPSYIRATGI VQMRNAVHEN EADMPLRQKM RERVQPKMGK LDIDYQKLHD 300
AFFRYQTKPV LTGFGECYFE GKELEADVKE KRPGDISEEL REALGIAPGA PPPWLFAMQR 360
YGPPPSYPDL KIPGVNCPIP TGAQWGFHPG GWGKPPVDQF NRPLYGDVFG NVKPRIHAGT 420
GSPVSTQHWG ELEEFEEEES SEEEESEDVE YPTEEITERE TIEEYQSASE PRSQREDLHA 480
EPLTYFNQSN VEVDNVELRK NTQPSSDAAN RDLYQVLPEK STNISGFMGP QHQYDIPTAE 540
DTLPQKRNAH SMLSSTNKGD VALNQSSNWQ DELSELVSEQ AMKVGAAKRQ KTQSKRDKFR 600
L 602
Keyword

KW-0143--Chaperone
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0747--Spliceosome

Interpro

IPR007180--DUF382
IPR006568--PSP

PROSITE
Pfam

PF04037--DUF382
PF04046--PSP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005686--C:U2 snRNP
GO:0071004--C:U2-type prespliceosome
GO:0003723--F:RNA binding
GO:0000245--P:spliceosomal complex assembly