dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0040923 | ||||||||
| Uniprot Accession | Q9UUI2; SHF1_SCHPO; | ||||||||
| Genbank Protein ID | NP_594735.1; | ||||||||
| Genbank Nucleotide ID | NM_001020163.2; | ||||||||
| Protein Name | Small histone ubiquitination factor 1 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | shf1 | ||||||||
| Gene Synonyms/Alias | SPAC22F8.12c; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Component of the histone H2B ubiquitin ligase complex (HULC) which plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MSSRRNDYHY DGNDHQYRSP LKSNVDQNSF YESSYRSRQS YHQRTKTPRS SYDSPSSSTN 60 SKEHNSPYHY RVPSNNSTRA SFGAASTDTN VELPKINLPD SSLSSKLQSC KSACENSSQS 120 LLNVEQQYAQ QVHFWEKIRT DIYREGLRSD AAVKSLNDFV NNVSF 166 |
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| Keyword | KW-0156--Chromatin regulator |
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| Interpro | |||||||||
| PROSITE | |||||||||
| Pfam | |||||||||
| Gene Ontology | GO:0005829--C:cytosol |