dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0040920 | ||||||||
| Uniprot Accession | Q9UUG9; TSC2_SCHPO; | ||||||||
| Genbank Protein ID | NP_592909.1; | ||||||||
| Genbank Nucleotide ID | NM_001018309.2; | ||||||||
| Protein Name | Tuberous sclerosis 2 protein homolog | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | tsc2 | ||||||||
| Gene Synonyms/Alias | SPAC630.13c; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Together with tsc1, required for uptake of various amino acids from the environment and for proper conjugation. Involved in induction of gene expression of permeases and genes required for meiosis upon nitrogen starvation. May act as a GTPase-activating protein (GAP) for the small GTPase rhb1. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MNNKSLLDLS SEPAIKDTDI LSYFDANLPF KKRHQIVRSI YHGLKYYIYS STSIIQVWQN 60 IQDFISTKND NAAFRELVYN LMMRYVSTQK HLSIIERHTF FQTIEKDPFQ DIAELQLRLK 120 SLSVLTDEGH KISGIENRVG PLLSAWFNQY LQWQSQATEL QGKDADSKLV HLLFFKSLFK 180 FSTNLVKFQW FLVPEPQMLQ LVNSVVQICN HARLEDVVTE VLMFFDSMIR YSVIPKASLY 240 DTVLILCSTY ISTYSYSKLA QSVIFNLISS PVSNLAFENV FNILQYNRSN VNAVRGAVRL 300 MRFLMLQEVK NDAIASITLS SSIEFTEFPL GFNENVDFEI LGTVYLFLRT PSILNRLNFL 360 DWHRILNILM YCSQYLPLKA STSKEAFSKT AAFANIYDRV LDFLDFEALI PLLQQFQVKL 420 VFFLKDVLPV LKPKIRKKLL RLFETYNLIF PCNQYWVFNL EFLLGIYQCK TFDLEDRALL 480 FKLVEDACSV ADENSAPILC SKFLFPVIES FSKESDDCVV SPVYNMLFFL SVNFQNPGLK 540 DCIDHIFQQL ISDTSSVTVR RLATSTLIRL FYYYYDLRDA VPIQETLAKM LEILETPSFP 600 FVSRMLCLQF FLRFRANGTS IYICENIDLN EPFKVLNVDS ELIPAVYPIS DSFVNSATVE 660 KHIWERKEND LIKISNHSTE YGKDFVTFPT SSLLRFYRKS MATESNWTIL MFMITHLADQ 720 ISNRSMFIGA LEEIYNLLDF MCDIVFERVS ISAEIPSNIR KANIMIPILQ NVQMLFVYHD 780 QFSRAQEDEL VSVFFAGLQK WNEACHVSIH SLMLCCYELP VSIRKQLPAI LVTLSRLITK 840 PDLSVHILEF LCSLARLPDL IANFTDADYR QIFAIALKYI QHRDFTKESK DSNDTESILK 900 NSYSSYVLAL AYSVLQIWFL SLRLTERKKF VPWILRGLKL ASEGKPLEDL CLVQYDMMQQ 960 FCYSNSDINN QTSTFVDSDV ESETWIRGNS LFTINVSVNS GFLEAVIRRP TGTTQYTFRN 1020 EASLQKFLWE ENLTSSKALT RGLLCTPSSF VSHFLDPHGI SLYNQPLLLP SNDDSVRRAI 1080 SVFDRIPVIE SLKAGLVYVG YQQRREADIL ANTNPSEDFL TFLNGLGTLF ELKTDQKVFA 1140 GGLDRENDID GAFAYCWKDK VTQMVFHCTT MMPTNIEHDP GCTLKKRHIG NDFVTIIFNE 1200 SGLEYDFDTI PSQFNFVNIV ITPESESIRR TGRQIKFYKV KALTKYDIDF SLFRRYKIVS 1260 SDALPAIVRD VTLNAAVFSH IYHRSAGDYV HIWAERLRQL KRLREKFQAS VLPEDYNLDE 1320 QTKTKLQNGT NFSDFTSYL |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR000331--Rap_GAP_dom |
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| PROSITE | PS50085--RAPGAP |
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| Pfam | |||||||||
| Gene Ontology | GO:0005737--C:cytoplasm |