dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040919
Uniprot Accession Q9UUG8; TUP12_SCHPO; O14432;
Genbank Protein ID NP_592910.2;
Genbank Nucleotide ID NM_001018310.2;
Protein Name Transcriptional repressor tup12
Protein Synonyms/Alias
Gene Name tup12
Gene Synonyms/Alias tup1;SPAC630.14c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Transcriptional repressor.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
135KTKHGRNSVSFGKYGdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MLFLVISQTT SFMITVRQFT FTIFKFQFMA TSNVSSRVNE LLEAVKKEFE DICQKTKTVE 60
AQKDDFEYKA MISAQINEMA LMKQTVMDLE MQQSKVKDRY EEEITSLKAQ LEARRKEIAS 120
GVVPQSSKTK HGRNSVSFGK YGNAGPFNSD NSSKPLILNN GSSGGTPKNL RSPAIDSDGT 180
VLAPIQTSNV DLGSQYYSSP HVRPAVGATM AGSAMRTFPS NLPLGHPPPP SDSANSSVTP 240
IAAPLVVNGK VSGNPPYPAE IIPTSNVPNR EEKDWTVTSN VPNKEPPISV QLLHTLEHTS 300
VICYVRFSAD GKFLATGCNR AAMVFNVETG KLITLLQEES SKREGDLYVR SVAFSPDGKY 360
LATGVEDQQI RIWDIAQKRV YRLLTGHEQE IYSLDFSKDG KTLVSGSGDR TVCLWDVEAG 420
EQKLILHTDD GVTTVMFSPD GQFIAAGSLD KVIRIWTSSG TLVEQLHGHE ESVYSVAFSP 480
DGKYLVSGSL DNTIKLWELQ CVSNVAPSMY KEGGICKQTF TGHKDFILSV TVSPDGKWII 540
SGSKDRTIQF WSPDSPHSQL TLQGHNNSVI SVAVSPNGHC FATGSGDLRA RIWSYEDL 599
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR013890--Tscrpt_rep_Tup1_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08581--Tup_N
PF00400--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0043234--C:protein complex
GO:0042393--F:histone binding
GO:0071473--P:cellular response to cation stress
GO:0043156--P:chromatin remodeling in response to cation stress
GO:0006342--P:chromatin silencing
GO:0045014--P:negative regulation of transcription by glucose
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated