dbPAF Protein Information
| Tag | Content | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0040907 | ||||||||||||
| Uniprot Accession | Q9UUA4; SEC66_SCHPO; | ||||||||||||
| Genbank Protein ID | NP_595471.1; | ||||||||||||
| Genbank Nucleotide ID | NM_001021381.2; | ||||||||||||
| Protein Name | Translocation protein sec66 | ||||||||||||
| Protein Synonyms/Alias | |||||||||||||
| Gene Name | sec66 | ||||||||||||
| Gene Synonyms/Alias | SPBC409.21; | ||||||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||||||
| NCBI Taxa ID | 284812 | ||||||||||||
| Functional Description (View all) |
Acts as component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and bip1 in a channel-forming translocon complex. A cycle of assembly and disassembly of Sec62/63 complex from sec61 may govern the activity of the translocon. sec66 is required to attach or retain sec72 in the sec63 complex (By similarity). | ||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 2
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| Sequence (Fasta) | MVSIYVPLIY ITILMGSMYG VSRFVRKSKN QESKPVSEEW FGENYSRNIF FSLLQQNPPA 60 EDTLLKAALV LRATEGLRRL MKLKVSRMAL NNLLNRGGVG DELIRKFGRL EKETELELMD 120 IAKTANSLQP GWNQFIFQTC NEIIENEKIH SIIDNIPKDI DSISQRWQTE KILYEAADEE 180 LRIQAQKELG VL 193 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR018624--Sec62/63_Sec66 |
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| PROSITE | |||||||||||||
| Pfam | PF09802--Sec66 |
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| Gene Ontology | GO:0005783--C:endoplasmic reticulum |