dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040898
Uniprot Accession Q9UU76; PUF6_SCHPO;
Genbank Protein ID NP_588564.1;
Genbank Nucleotide ID NM_001023551.2;
Protein Name Pumilio homology domain family member 6
Protein Synonyms/Alias
Gene Name puf6
Gene Synonyms/Alias SPCP1E11.11;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
RNA-binding protein involved in post-transcriptional regulation.
Phosphorylation Sites
dbPAF PTMs: 5
PositionPeptidesSourceReferences ( PMIDs )
34KLPKKVDSFSPKKKKdbPTM 3.0;UniProt18257517; 16381945; 23193290
36PKKVDSFSPKKKKNTdbPTM 3.0;UniProt18257517; 16381945; 23193290
79DFAGFGESASENDELdbPTM 3.0;UniProt18257517; 16381945; 23193290
81AGFGESASENDELESdbPTM 3.0;UniProt18257517; 16381945; 23193290
88SENDELESAESEAENdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MAIGKRKEST EVKKKDGSMN KRVKVAKLPK KVDSFSPKKK KNTTSSGSSE SDSMSQNDKK 60
KDSSLNESED EDFAGFGESA SENDELESAE SEAENDEESS SQKSNSKESH AQRKKLQKER 120
KAMKPFADTS LKAKSLWDKL RQKTSIKAEE RKTIIAELFD LIRTNVKQLV FKHDMSRVVQ 180
TCVKFGSKQQ RETICAELAG SYVDLCKSPY GKYLAIKIFK YGTPKMKEVI LGEMYGNVVK 240
MIRHREAAYV VEDAFREFTN LQQQRALICE FYGPEFQVFK DRTQDIHIDK LLIDHPEKRP 300
SIMQNLWKTI EGSIAKGSIG FTMVHRAMLE FINHADSNEA KELLNLTKEL IYEFVHTRDG 360
SQVAMKLFAL ANAKDRKVML KSLRPYLIET AKDSYGHLVV VAALDCTDDT IMTGKLLQAE 420
FEGELLKLSA DKFARRILLY VLVGWEDARY FSKENRELLR SLDSLKAKTS KKDPIVRRNE 480
LKATIGPLLI SLISKAAGDM IAESLASQVL VDALLYAPCE KEEAVDATLK AFDGNPEQDN 540
HLIHQIHCSR ALKTLVQNGH WSGAEKQVVK AEDDLKVASK LIVIIKKYLV EWASGDGAFV 600
VVAVLEALSD SEKQEFLKIL RKHKNQLNKS EFRGTKKLLE ML 643
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0694--RNA-binding
KW-0810--Translation regulation

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR012959--CPL_dom
IPR001313--Pumilio_RNA-bd_rpt

PROSITE

PS50302--PUM
PS50303--PUM_HD

Pfam

PF08144--CPL

Gene Ontology

GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0003730--F:mRNA 3'-UTR binding
GO:0003729--F:mRNA binding
GO:0000900--F:translation repressor activity, nucleic acid binding
GO:0017148--P:negative regulation of translation
GO:0006417--P:regulation of translation
GO:0042273--P:ribosomal large subunit biogenesis