| Tag |
Content |
| dbPAF ID |
dbPAF-0040897 |
| Uniprot Accession |
Q9UTR5; RGF2_SCHPO;
|
| Genbank Protein ID |
NP_594853.1;
|
| Genbank Nucleotide ID |
NM_001020282.2;
|
| Protein Name |
Rho1 guanine nucleotide exchange factor 2 |
| Protein Synonyms/Alias |
|
| Gene Name |
rgf2 |
| Gene Synonyms/Alias |
SPAC1006.06; |
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Stimulates the exchange of Rho1 and Rho5 GDP-bound form into GTP-bound form. Controls septum formation, cell wall synthesis and localization of F-actin patches.Functional Description
Stimulates the exchange of Rho1 and Rho5 GDP-bound form into GTP-bound form. Controls septum formation, cell wall synthesis and localization of F-actin patches. |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MLRNGAQNGN INSESHESFG KAAKGFRIFS SFSSSQKLFQ RRSSGSITHS PTALSSTTSL 60
NENDGNHFRP ASSLSFSPSS LSRKDSGPGD GLEVNKKNNF YRRSSSTDDF GISHARSRKE 120
IQSLGRPHTR QSFSVSDVSN GSSYPNIRKN SVHVNAPMPS FPEGSTAVLL KHHSGSKSAS 180
AISNIAPSHS NSTSSRRPYI HPAFLSQVAV EFRKRLNIGD RVKDGLLYKD AFLGSEAVDV 240
LMHIVRTTDR NLALLLGRAL DSQKMFHDVT YSHRLRDSLK EVYQYRRIIS PPPGLSSMDS 300
NGSSIENNFL YTKRRANTSD SFDSVLSDSS TTPTISSSVQ VNSLAFITSS LSAITKEPEA 360
PETEYNPHGV FTLLTECYSS TCSRNRLCYS ISCPRRLEQQ ARLHLKVQPV LSGGSTSITD 420
KQEEDHRLWS ENVPKQVVDQ IDVREWKRQE IIFEVIYTER DFVRDLEYIR DFWIKPLSTS 480
NVIPENNRQQ FIRCVFHNIM QIHAVNSRLS NALNRTQTLQ PVVNTIGDLF LDYVPKFEPF 540
IKYGANQAIA KFEFEREKST NRNFANYVHE VERLRESRKL ELNGYLTKPT TRLARYPLLL 600
SGVLKYTDKD NPDTENIPRV IEMIREFLTK LNYETGKTEN RLSLLQLNEQ LSCSPADRAK 660
LTLFDPSRLL IFKGVVKLKA SSYSNGDTEN DIHMFLLDNF LLLCKIKIQM KRRVHKLHLR 720
PLPLELLSIS YIEDSPSRGS LPRRPSSALL TNPISITKSN PPPVKAYGLQ LVFIGARGFS 780
ISLYLNTLIA RDQWKQHIEK QQDIIRKRHL VFESRGICCQ SWFTGNKLLC AVAYDAGRKL 840
LFGTYKGLYI SSRKSNNGSC LEPIFKLQLP NISQLDVIEE HNVLLLLAEK ILYELPLDAL 900
DSVEQINSKS LRRVTGHVSF VKTGFCMQRI LVCAVKSTVL NTTLRIYEAD RALKNKKTQS 960
LKKPFGNQAT LKIFTEVQMP MEALSVHFLK TKLCVGSFKG FDIISLENAV FQSLLNPADT 1020
SFRFLEKRED IRPIAMFRLR GEFLLCYSDF AFFVNTNGWK SRQSWMINWE GQPQGCALCY 1080
PYILAFEPDF IEIRNAETAE LVQIIMGQNI KLLTDGRGLI SEGGEILYST EPIPFSSGEN 1140
PIVHSLILPP ANAAGPAL
1159Fasta Sequence
>Q9UTR5|rgf2|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MLRNGAQNGNINSESHESFGKAAKGFRIFSSFSSSQKLFQRRSSGSITHSPTALSSTTSLNENDGNHFRPASSLSFSPSSLSRKDSGPGDGLEVNKKNNFYRRSSSTDDFGISHARSRKEIQSLGRPHTRQSFSVSDVSNGSSYPNIRKNSVHVNAPMPSFPEGSTAVLLKHHSGSKSASAISNIAPSHSNSTSSRRPYIHPAFLSQVAVEFRKRLNIGDRVKDGLLYKDAFLGSEAVDVLMHIVRTTDRNLALLLGRALDSQKMFHDVTYSHRLRDSLKEVYQYRRIISPPPGLSSMDSNGSSIENNFLYTKRRANTSDSFDSVLSDSSTTPTISSSVQVNSLAFITSSLSAITKEPEAPETEYNPHGVFTLLTECYSSTCSRNRLCYSISCPRRLEQQARLHLKVQPVLSGGSTSITDKQEEDHRLWSENVPKQVVDQIDVREWKRQEIIFEVIYTERDFVRDLEYIRDFWIKPLSTSNVIPENNRQQFIRCVFHNIMQIHAVNSRLSNALNRTQTLQPVVNTIGDLFLDYVPKFEPFIKYGANQAIAKFEFEREKSTNRNFANYVHEVERLRESRKLELNGYLTKPTTRLARYPLLLSGVLKYTDKDNPDTENIPRVIEMIREFLTKLNYETGKTENRLSLLQLNEQLSCSPADRAKLTLFDPSRLLIFKGVVKLKASSYSNGDTENDIHMFLLDNFLLLCKIKIQMKRRVHKLHLRPLPLELLSISYIEDSPSRGSLPRRPSSALLTNPISITKSNPPPVKAYGLQLVFIGARGFSISLYLNTLIARDQWKQHIEKQQDIIRKRHLVFESRGICCQSWFTGNKLLCAVAYDAGRKLLFGTYKGLYISSRKSNNGSCLEPIFKLQLPNISQLDVIEEHNVLLLLAEKILYELPLDALDSVEQINSKSLRRVTGHVSFVKTGFCMQRILVCAVKSTVLNTTLRIYEADRALKNKKTQSLKKPFGNQATLKIFTEVQMPMEALSVHFLKTKLCVGSFKGFDIISLENAVFQSLLNPADTSFRFLEKREDIRPIAMFRLRGEFLLCYSDFAFFVNTNGWKSRQSWMINWEGQPQGCALCYPYILAFEPDFIEIRNAETAELVQIIMGQNIKLLTDGRGLISEGGEILYSTEPIPFSSGENPIVHSLILPPANAAGPAL
|
| Keyword |
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0344--Guanine-nucleotide releasing factor
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0717--Septation
|
| Interpro |
IPR001180--CNH_dom
IPR000591--DEP_dom
IPR000219--DH-domain
IPR011993--PH/PTB_dom
IPR001849--PH_domain
IPR011991--WHTH_DNA-bd_dom
|
| PROSITE |
PS50219--CNH
PS50010--DH_2
|
| Pfam |
PF00780--CNH
PF00610--DEP
PF00621--RhoGEF
|
| Gene Ontology |
GO:0000935--C:barrier septum
GO:0051285--C:cell cortex of cell tip
GO:0030428--C:cell septum
GO:0005829--C:cytosol
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0051666--P:actin cortical patch localization
GO:0030476--P:ascospore wall assembly
GO:0000917--P:barrier septum assembly
GO:0009272--P:fungal-type cell wall biogenesis
GO:0035556--P:intracellular signal transduction
GO:0043547--P:positive regulation of GTPase activity
GO:0060622--P:regulation of ascospore wall beta-glucan biosynthetic process
GO:0043087--P:regulation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction
|
