dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0040893
Uniprot Accession Q9UTP9; DBP4_SCHPO;
Genbank Protein ID NP_594652.1;
Genbank Nucleotide ID NM_001020081.2;
Protein Name ATP-dependent RNA helicase dbp4
Protein Synonyms/Alias
Gene Name dbp4
Gene Synonyms/Alias SPAC1093.05;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 ATP-dependent RNA helicase required for ribosome biogenesis. Involved in the release of U14 snoRNA in pre-ribosomal complexes. Required for pre-rRNA cleavage at site A2 (By similarity).
Phosphorylation Sites
 dbPAF PTMs: 4
PositionPeptidesSourceReferences ( PMIDs )
500KDYNSSTSLDSSEESdbPTM 3.0;UniProt18257517; 16381945; 23193290
503NSSTSLDSSEESEVDdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
504SSTSLDSSEESEVDVdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
545QRLVEVNSDEDDGDFdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
Sequence
(Fasta)		MPKNRTGRSR EAREKKRKEE EEEIEELNSQ IEALSETVDH FAELPLTQPT KSALKNAHFI 60
TLTEIQKQCI PSALKGRDIL GAAKTGSGKT LAFIVPLIEN LYRKKWTSLD GLGALVISPT 120
RELAIQTFET LVKIGRLHSF SAGLIIGGNN YKEEKERLSR MNILVCTPGR LLQHIDQAVN 180
FDTSGLQMLI LDEADRILDM GFRTTLDAIV SSLPVHRQTM LFSATQTKSV KDLARLSLQN 240
PDFISVHEND TSSTPSNLNQ FYLTVPLTEK LDILFGFIRT HLKFKTIVFL SSCKQVRFVY 300
ETFRRMRPGI SLLHLHGKQK QTTRTEVTAK FTSSRHVVLF CTDIVARGLD FPAVDWVIQL 360
DAPEDVDTYI HRVGRTARYN RSGNALLLLL PSEEAFLKRL ESKKIAVERI NVKDGKKTSI 420
RNQLQNLCFK DNDIKYIGQK AFISYLRSIY LQKDKDVFQL DKLPVEAFAD SLGLPGTPKI 480
TFGKLKNHSQ SQKDYNSSTS LDSSEESEVD VENKQNVRTK YDRIFERKNQ DVLAAHRQRL 540
VEVNSDEDDG DFLQVKRVDH DLPEETGERF NANSKRKEKM ASSKKAMLKY KKSADKVYFD 600
DEGNAIPFYA MNTEDTFQKA GDPAALIASH LAEERKALEK ADITDKETVR QKQLEKKRRR 660
QELERITQQD ATPDEYVPEG PIVAFVDDEL PETSKKQKKW FEDNDERDHG GIVEVENLNS 720
LEDQEALALK LMGAA 736
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0690--Ribosome biogenesis
KW-0694--RNA-binding
KW-0698--rRNA processing
Interpro

IPR011545--DEAD/DEAH_box_helicase_dom
IPR025313--DUF4217
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000629--RNA-helicase_DEAD-box_CS
IPR014014--RNA_helicase_DEAD_Q_motif
PROSITE

PS00039--DEAD_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51195--Q_MOTIF
Pfam

PF00270--DEAD
PF13959--DUF4217
PF00271--Helicase_C
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004004--F:ATP-dependent RNA helicase activity
GO:0003723--F:RNA binding
GO:0010501--P:RNA secondary structure unwinding
GO:0006364--P:rRNA processing