dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0040892
Uniprot Accession Q9UTN6; SNF21_SCHPO; O14024;
Genbank Protein ID NP_594861.1;
Genbank Nucleotide ID NM_001020290.2;
Protein Name Chromatin structure-remodeling complex subunit snf21
Protein Synonyms/Alias ATP-dependent helicase snf21;RSC complex subunit snf21;
Gene Name snf21
Gene Synonyms/Alias SPAC1250.01;SPAC29A4.21;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Helicase. Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. Controls particularly membrane and organelle development genes.
Phosphorylation Sites
 dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
998GRGARRRTPVVYDEAdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)		MRAEKQYTRN EVEETIVRWK KLKESGATEH DNTEYAQLCD VLRSAQSEIE ARRDLKGHIK 60
RCFSSVDKNT EKLILKQQVL AYKKLSQNLP APDDCILSVL LRLSKDEQLL QSIVKQPLQN 120
SKVDGKVRRD FGSCQITPSA KQQRKYLQYQ ISEDDAIKNR MFRRMSDLES YPAVMRDVAE 180
LKDDNERLNL DTIKRNALVE LKKLRLIKQQ ESLRHQVMHC QPHLRTIVNA VERMSCRRPK 240
LVPQATRLTE VLERQQRSDR ERRLKQKQCD YLQTVCAHGR EINVRTKNAQ ARAQKANRAV 300
LAYHSHIEKE EQRRAERNAK QRLQALKEND EEAYLKLIDQ AKDTRITHLL RQTDHYLDSL 360
AAAVKVQQSQ FGESAYDEDM DRRMNPEDDR KIDYYNVAHN IREVVTEQPS ILVGGKLKEY 420
QLRGLQWMIS LYNNHLNGIL ADEMGLGKTI QTISLITHLI EKKRQNGPFL VIVPLSTLTN 480
WTMEFERWAP SIVKIVYKGP PQVRKALHPQ VRHSNFQVLL TTYEYIIKDR PLLSRIKWIY 540
MIIDEGHRMK NTQSKLTNTL TTYYSSRYRL ILTGTPLQNN LPELWALLNF VLPRIFNSIK 600
SFDEWFNTPF ANTGGQDKME LTEEESLLVI RRLHKVLRPF LLRRLKKDVE AELPDKVEKV 660
IRCQMSGLQQ KLYYQMKKHG MLYVEDAKRG KTGIKGLQNT VMQLKKICNH PFVFEDVERS 720
IDPTGFNYDM LWRVSGKFEL LDRILPKLFR SGHRILMFFQ MTQIMNIMED YLHYRQWRYL 780
RLDGSTKADD RSKLLGVFND PTAEVNLFLL STRAGGLGLN LQTADTVIIF DSDWNPHQDL 840
QAQDRAHRIG QTKEVRIYRL ITEKSVEENI LARAQYKLDI DGKVIQAGKF DNKSTPEERE 900
AFLRSLLENE NGEEENDEKG ELDDDELNEI LARGDDELRL FKQMTEDLER ESPYGKNKEK 960
ERLIQVSELP EFYQREEPEK TTDLLQEEPL GRGARRRTPV VYDEAVRDAQ WMAEMDMESE 1020
ARPTRGRPKR NIASVDETPA LTLNGKPKKK RGPAPDTLTS EHRSLLRRVC LEIYKAVNEL 1080
EDDNGRPLNK LFLELPSKKL YPDYYMIIKS PIALDAIRKH INGTFYKTLE AMKSDLMTMF 1140
NNARTYNEEG SFVYEDANKM QTAMETKIEE LEEDGTLATL RGMEAEATSQ LEDRIENEA 1200
Keyword

KW-0067--ATP-binding
KW-0103--Bromodomain
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR014012--HSA_dom
IPR027417--P-loop_NTPase
IPR029295--SnAC
IPR000330--SNF2_N
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51204--HSA
Pfam

PF00439--Bromodomain
PF00271--Helicase_C
PF07529--HSA
PF14619--SnAC
PF00176--SNF2_N
Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0016586--C:RSC complex
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0003677--F:DNA binding
GO:0000991--F:transcription factor activity, core RNA polymerase II binding
GO:0006338--P:chromatin remodeling
GO:0032508--P:DNA duplex unwinding
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter