dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040891
Uniprot Accession Q9UTN3; CID14_SCHPO; Q09876; Q565C4;
Genbank Protein ID NP_001018181.1;
Genbank Nucleotide ID NM_001018285.2;
Protein Name Poly(A) RNA polymerase cid14
Protein Synonyms/Alias
Gene Name cid14
Gene Synonyms/Alias SPAC12G12.13c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Required for 3' polyadenylation of the 5.8S and 25S rRNAs as a prelude ot their degradation in the exosome. Involved in the nucleolar organization to ensure faithful chromosome segregation during mitosis.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
163FIKFDWNSDEDEDSVdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MGKKSVSFNR NNYKKRKNER TEPLPRRIFK NDKPSKFKSK RKEKDKNSDA YDEMLLNNNF 60
TLLDQEEPMV EIGSKKSRND NDSEGIRDKG GVEISNKNDP YIQFGKADPL EPLEKPDLPE 120
EAIKRGEPTI LLGIPKREGR KTNPVHDKAV ENNSDFIKFD WNSDEDEDSV SNDKSKNNES 180
LKKSSKNEIP GFMRQRGRFF HEANEKSDSN RKRKRQAYEL DSQSCPWHRQ YKVEREVSRI 240
FHQDILHFID YITPTPEEHA VRKTLVSRIN QAVLQKWPDV SLYVFGSFET KLYLPTSDLD 300
LVIISPEHHY RGTKKDMFVL AHHLKKLKLA SEVQVITTAN VPIIKFVDPL TKVHVDISFN 360
QPGGLKTCLV VNGFMKKYPA LRPLVIIIKH FLNMRALNEV FLGGLSSYAI VCLVVSFLQL 420
HPRLSTGSMR EEDNFGVLLL EFLELYGKQF YYDAVGIAVH NGGFYFSKKK MGWLKPNQPY 480
LLSIQDPVDF QNDVSKSSRG LLRVKATFAN GFDLLTSKLY ALASRIEREG VNRVKDFPSI 540
LSTILSVDEG VRQHREHMLK CYKNNPVPLE PLVEVDALAS IDVDKLPLQD VGLQYVEDES 600
DSDETDAAKD DLFKVNESIE TNGHENFQKQ ALTSTGEQSS SNSRANPSKL FNISSDDSED 660
EVPIIEDTTA SDEESRAKKI RKRF 685
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0460--Magnesium
KW-0464--Manganese
KW-0479--Metal-binding
KW-0507--mRNA processing
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0694--RNA-binding
KW-0808--Transferase

Interpro

IPR002058--PAP_assoc
IPR002934--Polymerase_NTP_transf_dom

PROSITE
Pfam

PF01909--NTP_transf_2
PF03828--PAP_assoc

Gene Ontology

GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0031499--C:TRAMP complex
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0004652--F:polynucleotide adenylyltransferase activity
GO:0043023--F:ribosomal large subunit binding
GO:0003723--F:RNA binding
GO:0006397--P:mRNA processing
GO:0043630--P:ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
GO:0071035--P:nuclear polyadenylation-dependent rRNA catabolic process
GO:0006396--P:RNA processing
GO:0016077--P:snoRNA catabolic process
GO:0016078--P:tRNA catabolic process