dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040888
Uniprot Accession Q9UTM3; RPN5_SCHPO; O14381;
Genbank Protein ID NP_593278.1; NP_594776.1;
Genbank Nucleotide ID NM_001018674.2; NM_001020204.2;
Protein Name 26S proteasome regulatory subunit rpn5
Protein Synonyms/Alias
Gene Name rpn502
Gene Synonyms/Alias rpn5a;SPAC1420.03;rpn5b;SPAPB8E5.02c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Required for proper proteasome assembly.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
209FEKEDVQSLKLKYYEdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MEQKPEVDYS EKFAELQKSL NNLNTIDIDA NLEKLLIFEK QVRQASDTST NTKVLIYIAD 60
LLFRAGDFQG LNEQLVSLFK KHGQLKQSMT SLVQHVMTYL PGIDDLKTKI NLIETLRTIT 120
DGKIYVEVER ARLTQLLSQI KEEQGDIKSA QEILCNEPVE TYGSFDLKEK VAFILDQVRL 180
FLLRSDYYMA STYTKKINVK FFEKEDVQSL KLKYYEQKIR IGLHDDAYLD VCKYYRAVYD 240
TAVVQEDPEK WKEILENVVC FALLTPYDNE QADLLHRINA DHKLNSLPLL QQLVKCFIVN 300
ELMRWPKIAE IYGSALRSNP VFAENDEKGE KRWSELRKRV IEHNIRVVAN YYSRIHCSRL 360
GVLLDMSPSE TEQFLCDLIA KHHFYAKIDR PAQVISFKKS QNVQEQLNEW GSNITELLGK 420
LEKVRQLIIK EEMMNSIQQA VAK 444
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0647--Proteasome
KW-1185--Reference proteome

Interpro

IPR000717--PCI_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE
Pfam

PF01399--PCI

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0005634--C:nucleus
GO:0008541--C:proteasome regulatory particle, lid subcomplex
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process