dbPAF Protein Information
| Tag | Content |
|---|---|
| dbPAF ID | dbPAF-0040883 |
| Uniprot Accession | Q9UTK4; NU189_SCHPO; P78796; |
| Genbank Protein ID | NP_594093.1; |
| Genbank Nucleotide ID | NM_001019517.2; |
| Protein Name | Nucleoporin nup189 |
| Protein Synonyms/Alias | Nuclear pore protein nup189; |
| Gene Name | nup189 |
| Gene Synonyms/Alias | SPAC1486.05; |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID | 284812 |
| Functional Description (View all) |
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. |
| Phosphorylation Sites |
dbPAF PTMs: 4 |
| Sequence (Fasta) | MFGQNNSSGF GGGTGAFGQN NQQTGGLFGS NSNTPGNTLF GSQNTSTTGF GQNTTQPLFG 60 SNTNGGLFGN RNNTTTTGGT GFGMSSGTGM FGQSNTPAFG GTNNATNPSG GGLFGSNTAN 120 NNANTGTSFS FGSNAGSTGF GSQGTGGGLF GSSTTPATTN AFGTSGFVSS NANAVNGTAN 180 PPYAVTSEKD PQTNGTSVFQ SITCMPAYRS YSFEELRLQD YNQGRRFGNA SSTNTTSAFG 240 STPAFGASTT PFGQNLSGTT NNATPFGTSN ATNTTPGSGL FGGGSAFGSN TTNTGFGSGT 300 NNASGGLFGQ NNNTTSTPST GLFGGSTFNQ QKPAFSGFGS TTNTTNTGTG TGLFGSNNAT 360 NTGTGQTTGG LFGGAATGTG TGFGSSTGGF GSNTNNQPNS GTMGTGLFGF GANNNTANNN 420 TAPTSTFGGN NSSNFSFGAN NNAATKPSGF GFGSTTTTPA SGGFSFGQNA NNAPKPAFGS 480 TATTAPKPAG TGLFGGLGAG ANTNTATNAT GTGGSLFGNA NTAGSNMFGS ANSSTPGTGL 540 FGSTQTNNAT SNTGTGLFGS NNANTTNTGG SLFNKPSTTT GGLFGNTTAQ QPSTTTSGLF 600 GASNTNNQAQ TSNFGTGLFG GSQAGQQQQP LQASIDQNPY GNNPLFSSTT SQVAPTSIQE 660 PIASPLTSKP TPKKAASLPQ FWLSPRSHNT ARLASISSFA KSAVMNSTSA SGKPKSLHLF 720 DSLNDDVLLS ADAFTPRQNI KKLVITHKIS KDDILQNGVK NGNDAKSDSK VQEKAPQNEA 780 DGSLKKDEHV VLSDDYWMKP SIEELSKYPK EKLCSVHQFS VGRTGYGQVA FLKPVDLSGF 840 EKLEDIPGKV VVFERKICAV YPVEGSSPPL GEGLNVPAII TLEKTWPLSR ETREPIKDPQ 900 NPRYIQHVKR LHRIKDTEFI DFNDGKWIFK VQHFSRYGLL DDEEEENDMS STSNEAGNLK 960 KYDQPNLKVS GKNDSFVTHH TPGAFPNDSK NKELNRHFLK VDDSAPLDDT FMSKKVKLDF 1020 SSDSNVSERG DYDDNAKKVD EVISIEKVDG YSKENNVPLS EDDLSNSSES SNESVYSLVE 1080 ESDASLAADN MDIEDISEES DREELSSMRF GAQDFHGLVV TDNWRDQLNL SVQRSALIKA 1140 AFPESQSNAN LKNSRGIYYN EHDLVTDIFG NQNLDTDRPW QSLDKPGAFI PSKFHFTANG 1200 SCIYVLKSSD VKIRSIYDFI PTKDPNGTKL LEYQLDQTEV YLDLSGTHAA SPRSSMTVKP 1260 LSLCSSGYES IVWDLTSILF DPKNYSLPSE LSSEAREVLY QKLVRESLSE WITKTLEHET 1320 TTLAKEAETS EERIYILLTG NLIGQACEEA VQSQNNRLST LIPLVNSDVD IQQEVKQQLE 1380 EWRKHGDLPF INKFTRLIFE LLSGNTDIAE GCGTKGDEDY VQSIPITKNM TWLRAFGLKL 1440 WYNTDISIGE AMQLYVESLQ KFPEIMQKPI ATSAVQGIEV YDIIYLLLKA YAMGTSLEEL 1500 TIPESAKCSP LNYRVVWQLA IYLSKARSLC DFSDRVVDIN MAEDLKPISV HSDQLTLAYA 1560 SQLEASGQWL WSLFVLLHLE NVETRTSTIT SCLARNLRGG LGAGAVEMIE KLCIPESWLN 1620 EAKALYARYV GDHLNELYFL QEAALYEDAH KVLLDTLAPQ AVISGNKTQL KKALEGFNGQ 1680 TDGLASWRFG GQIYSDYLDL LEGNFDANQE LKLFTLRKIS VALKELNATN LLQKAALHKI 1740 SRFVNALCNE ESLTDAICNL PLPLADSLAN LQNISVQF 1779 |
| Keyword | KW-0181--Complete proteome |
| Interpro | IPR025574--Nucleoporin_FG_rpt |
| PROSITE | PS51434--NUP_C |
| Pfam | |
| Gene Ontology | GO:0031965--C:nuclear membrane |