dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040881
Uniprot Accession Q9UTH0; NU132_SCHPO; Q9UU23;
Genbank Protein ID NP_593915.1;
Genbank Nucleotide ID NM_001019344.2;
Protein Name Nucleoporin nup132
Protein Synonyms/Alias Nuclear pore protein nup132;
Gene Name nup132
Gene Synonyms/Alias nup133b;SPAC1805.04;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
17NEEVVSFSPLKRISVdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MSSILGKRKN EEVVSFSPLK RISVEKSLLD STAYNNSLDW LRSKNFKVSC LLKHFNSKII 60
NDHPLSGSCY TDIGYALINS RKACFILSYR QSLGTAEPPT ITFPLPEEDS NGFSGQNALT 120
AFVPSDASDK EPGLLIVMPI SGRIAYWTSI GNALAQSYIC PQGMESLIKL LPKEKCEHLC 180
CSNPMKFIIS TNFGRLFSVQ LRDPAGQPDV SVQLFASDIS TFSTILQKMK IFNYPSIHII 240
ALKSPPLFSP YQHLLYVAEA SGLLEIYDLK LENKLVSGMN LSPIFKQVLR EGCPDASGLE 300
VLDLTICPTN GNLVSFLVCW KNSINYRYMI ISLDFSDISS PSVMNIHPLY SFSSKSLESS 360
KLHYSSSGNS LFVVLTDAVI IVHVQEDDKD IVSRTSWEEV IRMNTNVSGG IFMSTCYKYV 420
LGKYSIPTES CFIATPYSGI AEIEVHSLEH PANNESLVKS KLEEAVFYSF LPGNPIDFSC 480
NYLRSIKKPE LERIIVDLGM DILNSRSTHL PPLFASLMQH LSCRLNSLNN LVRYIRSMSL 540
DVDRQVLYKL RVMGEKCNSV RYLWNTIDTE FSTVSHSLIF QRIIYRLTQS ASSDNALREW 600
FLHNIESIDQ LIAQAHEFCI DSGSRVQELP LEVLDVIMEA NEVILAIQSS ALAYRRESQK 660
IYKLSIDTFG EEVPWTSTPE TLVLLCRQFE LTRSALVQSH QGTSDVENTF KIKDKGVLRN 720
VVSNLEVQLV ALTEVCFDAY SERIRWIEQR CGKDASEIQD VKEAFAVNRR FWVQTLSDIG 780
KGSSAIRIAE KYSDYRSLVE LCYQLYEDNE LTDALNNYLD LFGIKFAFIL YDYFVENGMA 840
LELLNSDRFN KSYLKQFFKS RDYNQISWMH DMRLGDYDAA SHRLLQLATK QEKLVDKKES 900
ELSLSKLFLY AVPSNSGNIR DLVLVEQKLE QLHIQKMVSK SVMPVVERLR SQGKKYQLVE 960
AVVDDLIGAK VAPVIARQVM QRVVKKFIAG QVVEATELLE YLSFSLYRRE DLVEGEVTDY 1020
YLALRLLLTT RLTDDAKRFY ENTIWRRAVL HDNWIQVLDT QGKNDAIIET QFRMSALYRT 1080
LEAVTINGLF HEGLIRPGSL SSCKFEGYDP QNLISIYPPA RFGDVTEVTK VLNRESVKLD 1140
HYLTKTNLNT CYISMCLSCD TI 1163
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR007187--Nucleoporin_Nup133/Nup155_C
IPR014908--Nucleoporin_Nup133/Nup155_N
IPR015943--WD40/YVTN_repeat-like_dom

PROSITE
Pfam

PF03177--Nucleoporin_C
PF08801--Nucleoporin_N

Gene Ontology

GO:0005635--C:nuclear envelope
GO:0031965--C:nuclear membrane
GO:0034399--C:nuclear periphery
GO:0005643--C:nuclear pore
GO:0031080--C:nuclear pore outer ring
GO:0016973--P:poly(A)+ mRNA export from nucleus