dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0040873 | ||||||||
| Uniprot Accession | Q9UTA5; TYW3_SCHPO; | ||||||||
| Genbank Protein ID | NP_594475.1; | ||||||||
| Genbank Nucleotide ID | NM_001019904.2; | ||||||||
| Protein Name | tRNA wybutosine-synthesizing protein 3 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | tyw3 | ||||||||
| Gene Synonyms/Alias | SPAC25B8.15c; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 (By similarity). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
|
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| Sequence (Fasta) | MNIKGIDVSF DAQKKEILEG LKSSVPDASP KGHPDSPIFP LLDVINSHPD WVTTSSCSGR 60 ISVYVQGANS RKGGGYWLFV SHQAHEELPP VLEDEKVEYG KVPSSPVEGN REIQYAFEPM 120 ILHVQTRSLA NAQHLQRVAA SCGFRETGIQ GSEQKFIVAI RTSLRMDIPI GCLTASEKLQ 180 FYITREYMCF LFKRSVEYFT ENGNRMARLK EQLERQVEKR MKPRRKLRNM DDYLVQS 238 |
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| Keyword | KW-0181--Complete proteome |
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| Interpro | IPR003827--tRNA_yW-synthesising |
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| PROSITE | |||||||||
| Pfam | PF02676--TYW3 |
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| Gene Ontology | GO:0005829--C:cytosol |