Tag |
Content |
dbPAF ID |
dbPAF-0040872 |
Uniprot Accession |
Q9UT97; PSA5_SCHPO; |
Genbank Protein ID |
NP_594372.1; |
Genbank Nucleotide ID |
NM_001019793.2; |
Protein Name |
Probable proteasome subunit alpha type-5 |
Protein Synonyms/Alias |
|
Gene Name |
pup2 |
Gene Synonyms/Alias |
SPAC323.02c; |
Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
NCBI Taxa ID |
284812 |
Functional Description (View all) |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).Functional Description
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).
|
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence (Fasta) | MFMTRSEYDR GVNTFSPEGR LFQVEYAIEA IKLGSTAIGV KTKDAVVLGV EKRLTSPLME 60 SHSVEKLFEI DSHIGCAISG LTADARTIIE HARVQTQNHR FTYDEPQGIE STTQSICDLA 120 LRFGEGEDGE ERIMSRPFGV ALLIAGIDEH GPQLYHSEPS GTYFRYEAKA IGSGSEPAKS 180 ELVKEFHKDM TLEEAEVLIL KVLRQVMEEK LDSKNVQLAK VTAEGGFHIY NDEEMADAVA 240 REQQRMD
248Fasta Sequence
>Q9UT97|pup2|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) MFMTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKDAVVLGVEKRLTSPLMESHSVEKLFEIDSHIGCAISGLTADARTIIEHARVQTQNHRFTYDEPQGIESTTQSICDLALRFGEGEDGEERIMSRPFGVALLIAGIDEHGPQLYHSEPSGTYFRYEAKAIGSGSEPAKSELVKEFHKDMTLEEAEVLILKVLRQVMEEKLDSKNVQLAKVTAEGGFHIYNDEEMADAVAREQQRMD
|
Keyword |
KW-0181--Complete proteome KW-0963--Cytoplasm KW-0378--Hydrolase KW-0539--Nucleus KW-0597--Phosphoprotein KW-0645--Protease KW-0647--Proteasome KW-1185--Reference proteome KW-0888--Threonine protease
|
Interpro |
IPR029055--Ntn_hydrolases_N IPR000426--Proteasome_asu_N IPR023332--Proteasome_suA-type IPR001353--Proteasome_sua/b
|
PROSITE |
PS00388--PROTEASOME_ALPHA_1 PS51475--PROTEASOME_ALPHA_2
|
Pfam |
PF00227--Proteasome PF10584--Proteasome_A_N
|
Gene Ontology |
GO:0005737--C:cytoplasm GO:0005829--C:cytosol GO:0005634--C:nucleus GO:0005839--C:proteasome core complex GO:0019773--C:proteasome core complex, alpha-subunit complex GO:0004175--F:endopeptidase activity GO:0004298--F:threonine-type endopeptidase activity GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
|