dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040872
Uniprot Accession Q9UT97; PSA5_SCHPO;
Genbank Protein ID NP_594372.1;
Genbank Nucleotide ID NM_001019793.2;
Protein Name Probable proteasome subunit alpha type-5
Protein Synonyms/Alias
Gene Name pup2
Gene Synonyms/Alias SPAC323.02c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity).
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
16DRGVNTFSPEGRLFQcurated22817900
55LGVEKRLTSPLMESHdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MFMTRSEYDR GVNTFSPEGR LFQVEYAIEA IKLGSTAIGV KTKDAVVLGV EKRLTSPLME 60
SHSVEKLFEI DSHIGCAISG LTADARTIIE HARVQTQNHR FTYDEPQGIE STTQSICDLA 120
LRFGEGEDGE ERIMSRPFGV ALLIAGIDEH GPQLYHSEPS GTYFRYEAKA IGSGSEPAKS 180
ELVKEFHKDM TLEEAEVLIL KVLRQVMEEK LDSKNVQLAK VTAEGGFHIY NDEEMADAVA 240
REQQRMD 248
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0645--Protease
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0888--Threonine protease

Interpro

IPR029055--Ntn_hydrolases_N
IPR000426--Proteasome_asu_N
IPR023332--Proteasome_suA-type
IPR001353--Proteasome_sua/b

PROSITE

PS00388--PROTEASOME_ALPHA_1
PS51475--PROTEASOME_ALPHA_2

Pfam

PF00227--Proteasome
PF10584--Proteasome_A_N

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005839--C:proteasome core complex
GO:0019773--C:proteasome core complex, alpha-subunit complex
GO:0004175--F:endopeptidase activity
GO:0004298--F:threonine-type endopeptidase activity
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process