dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0040868
Uniprot Accession Q9UT76; EI2BB_SCHPO;
Genbank Protein ID NP_593435.1;
Genbank Nucleotide ID NM_001018868.2;
Protein Name Probable translation initiation factor eIF-2B subunit beta
Protein Synonyms/Alias eIF-2B GDP-GTP exchange factor subunit beta;
Gene Name tif222
Gene Synonyms/Alias SPAC343.14c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Phosphorylation Sites
 dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
106ENEKLIVSSSNSSSPdbPTM 3.0;UniProt18257517; 16381945; 23193290
108EKLIVSSSNSSSPSQdbPTM 3.0;UniProt18257517; 16381945; 23193290
112VSSSNSSSPSQKRDIdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
Sequence
(Fasta)		MSTINVEHTY PAVSSLIADL KSRKVQGPFA VAVETALVMR QVISQTRWST VDQLIDTVRA 60
VGSTLVKAQP TEFSCGNIIR RILRLIREEY QELLKTADEN EKLIVSSSNS SSPSQKRDIP 120
SNEKLVQSHE PVSVQMYSSM LNLLGRPTLE SPTHSKTVGD SRVTGGMDMR AVIISGIQDV 180
IDELDKINTD IEVQSMDHLH SNEIILTQGC SKTVEAFLRF AAKKRKFSVI VAEGFPNNQK 240
GSHAMAKRLA QAGIDTTVIS DATIFAIMSR VNKVILGTHA ILGNGGLVTY SGAQLVAQAA 300
RHHATPVVVC SGIYKLSPVY PYDLESIIQL SSPDKIMSFN EGDLISRAEI LNPYYDYIPP 360
DLVDLFITNL GGYPPSYLYR IMNDTYDASD TIL 394
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0810--Translation regulation
Interpro

IPR000649--IF-2B-related
PROSITE
Pfam

PF01008--IF-2B
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005851--C:eukaryotic translation initiation factor 2B complex
GO:0005634--C:nucleus
GO:0005085--F:guanyl-nucleotide exchange factor activity
GO:0003743--F:translation initiation factor activity
GO:0002183--P:cytoplasmic translational initiation
GO:0043547--P:positive regulation of GTPase activity
GO:0006446--P:regulation of translational initiation