dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0040855 | ||||||||
| Uniprot Accession | Q9USZ7; END3_SCHPO; | ||||||||
| Genbank Protein ID | NP_595720.1; | ||||||||
| Genbank Nucleotide ID | NM_001021618.2; | ||||||||
| Protein Name | Actin cytoskeleton-regulatory complex protein end3 | ||||||||
| Protein Synonyms/Alias | Endocytosis protein 3; | ||||||||
| Gene Name | end3 | ||||||||
| Gene Synonyms/Alias | SPBC11G11.02c; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MDPQEKNKYW EIFRGLNPEN GYLSGSKAAG VLRSSKLSSD KLEKIWDLAD IDDDGMFDFD 60 EFAIAMKITF DLINGVYKTV PDRVPEALVS TSKKHLVAAR DALRGNDDIA LLHKVPSLDT 120 DPEDAVLKDG FDWYISPSDK IRYSDIYSLH CNKHGEVSFN GLAPVFTPFG VPNSQIQKAW 180 KLVNPQGTET IQKDQCLVFL HILTQRSNGF RIPNDVPYSL KASFKRGNID YNLDSYNSTN 240 NYYSSPTMAP STGGAKPKSD LDAPRDVRDS DWELISLRNE LSKLDEKILS LQRETDDVNI 300 AQNKSKLIQR DLQKVLDYKL GILQSLKNDG PNGPSASAID NDLKMLEQQL NVLGRHLEGR 360 KSQVAKLEER LRSLS 376 |
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| Keyword | KW-0009--Actin-binding |
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| Interpro | IPR011992--EF-hand-dom_pair |
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| PROSITE | |||||||||
| Pfam | |||||||||
| Gene Ontology | GO:0030479--C:actin cortical patch |