dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040851
Uniprot Accession Q9USX3; RAD60_SCHPO;
Genbank Protein ID NP_595995.1;
Genbank Nucleotide ID NM_001021903.2;
Protein Name DNA repair protein rad60
Protein Synonyms/Alias
Gene Name rad60
Gene Synonyms/Alias SPBC1921.02;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Required for repair of DNA double strand breaks which occur during replication, or induced by UV or gamma radiation, via recombination between sister chromatids. This has a subsequent role in the maintenance of chromosome structure. May work in conjunction with the Smc5-Smc6 complex.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
111SCVTQPVSPVYNTRAcurated22817900
Sequence
(Fasta)
MDNLDEDDLA FFSKPIKKPP LNYAKQLIAS SSDSEEESEL DTNKQALEHI NAQKNITHNE 60
NKSAEPLSRQ STILDADEGN QDVSDTTPNA CLNEGRHSPK SAISCVTQPV SPVYNTRAAA 120
NLRNNSINSE AALSTTSSLL DDDFARRLEE IDRQVQEFEK SSSDMDVQIH THKREIEEDD 180
DNTSADVPLL KHSKSDHSTL YHSKSEFSTN EPVISVVLQL AVIGQRIPNS NISLPRDWEA 240
PLFFKVKSNQ QFRRVRIAYS ERKKVDNVVL VFQNQRLWDY GTPKGAGMLK VDTRLVVHAY 300
CHSDFISLKR IKELEVEKLS SVTEDSTAQT CKLITLLLRS SKSEDLRLSI PVDFTVKDLI 360
KRYCTEVKIS FHERIRLEFE GEWLDPNDQV QSTELEDEDQ VSVVLD 407
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0233--DNA recombination
KW-0234--DNA repair
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE
Pfam

PF11976--Rad60-SLD

Gene Ontology

GO:0005634--C:nucleus
GO:0000724--P:double-strand break repair via homologous recombination
GO:0031297--P:replication fork processing