dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0040850 | ||||||||
| Uniprot Accession | Q9USW9; SGF29_SCHPO; O74353; | ||||||||
| Genbank Protein ID | NP_596000.2; | ||||||||
| Genbank Nucleotide ID | NM_001021908.2; | ||||||||
| Protein Name | SAGA-associated factor 29 | ||||||||
| Protein Synonyms/Alias | |||||||||
| Gene Name | sgf29 | ||||||||
| Gene Synonyms/Alias | SPBC1921.07c;SPBC21D10.13; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Sgf11 is involved in transcriptional regulation of a subset of SAGA-regulated genes and is required for histone H2B deubiquitination (By similarity). | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
|
||||||||
| Sequence (Fasta) | MVRPINAEED VTSMWVKFHE SLNPIRSSLI KQEECYKTVD GDDNPIEERI KACDAGIQTS 60 EEQKKELEHT MQSLEMIINV LEKANEKPVI TNSPLTRSRR NRGTSFTANT VTFTPGMSVA 120 FKLPYTRHNE GGDWIQCIII KVTGEGAKQR FEVQDPEPDD DGNAGQIYKT TANHLIQIPA 180 KGTPLPPISP KTNVLARYPE TTTFYRAEVI RTLPDGSCKL RFEGEEEVGK ETVVERHLVL 240 EYNG 245 |
||||||||
| Keyword | KW-0181--Complete proteome |
||||||||
| Interpro | IPR010750--SGF29_tudor-like_dom |
||||||||
| PROSITE | PS51518--SGF29_C |
||||||||
| Pfam | PF07039--DUF1325 |
||||||||
| Gene Ontology | GO:0005829--C:cytosol |