dbPAF Protein Information
| Tag | Content | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0040844 | ||||||||
| Uniprot Accession | Q9USU1; EFC25_SCHPO; | ||||||||
| Genbank Protein ID | NP_596123.1; | ||||||||
| Genbank Nucleotide ID | NM_001022041.2; | ||||||||
| Protein Name | Ras guanine nucleotide exchange factor efc25 | ||||||||
| Protein Synonyms/Alias | Exchange factor cdc25p-like protein; | ||||||||
| Gene Name | efc25 | ||||||||
| Gene Synonyms/Alias | SPBC336.03; | ||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||
| NCBI Taxa ID | 284812 | ||||||||
| Functional Description (View all) |
Has a role in chromosome segregation and cell morphology upstream of the ras1-scd1 pathway. Promotes the exchange of ras1-bound GDP by GTP leading to its activation. | ||||||||
| Phosphorylation Sites |
dbPAF PTMs: 1
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| Sequence (Fasta) | MRRPNLDRLR LKSRQGFETS VSKPSTPSYS TYSLSPTFSD KSVLSPSTMS DSYALSSTYT 60 AGSSYQNGES DYFGSLPTPS SDKSSTSPFP YLKGSFDDRF SSTHSLTRQP SPRSPLTPLK 120 GNTRASPEIR YVSDFTPPSS PFEDMQASVH SLPLSGCSIG PVRTNHSSSL SNSSNSLLQT 180 ESSLRPNSSF VNSPFFPLPS SDDLFLNDRV INLFLFYEKF SYLFTHLLSA IKSRDALSIP 240 SLVLSLQEEL FNLCQQTGTF YLLQHNLLQN FEFENPIKLH FDKIIPYFSR LTVLTFSNRA 300 FIFPDHTFPR LQQSAEDFLY HLQFFFTLCA NNSLYLSRFC YYPSFVPNTP FGGKWTNNGL 360 SAVSSAYRTR LLEPCLPELD KCVWFLLKNC DEFIENFSDF ADEEYVFEIC STITSHSEQI 420 FNKLESWDMS IYFDKDLSEC EQATNFAVQS YFVTKQRCYD LLTDLVCSSQ DLMMEHSNDF 480 STMPTMIASI AVAFQTLFEN VCDFLKVRAA LVDEMQELAT KEFENKFSNA NTAKDDEPAR 540 QTNKGTTRIS RSSDFTAVSE MSKDTLTLGR NSLQSILMLD NLLTNKVVQS DNNVKGGTLP 600 ALVHYLVQNV HLNKDFRHSF LLTYKTFTTP QELFTLLVIL FHELPPPGLD ATAYSSWEKG 660 DNFVTKKNVC TVMNLWVQKY FFEDLKARNT LYLISEMRTF LRDHVVPSFH IGSVILSEID 720 NLWTEEPPDS LTQRLLSSPM ATFISLNVYA YTPEEFASQM TLLEFDYLKQ IPSREWIFRS 780 WVSRDSRSAV RNYINFSNCF TYWIINCILE KKNTKARTAV ISFFIQTAYK CLSLQNFSTL 840 MSIVSALNSA PIYRLHAAYK LVKAEDIICL SGLREIVETK KNFSTYRALL RKAELPCVPF 900 LGVILSDLTF IDEGNPDVLD SSPHLLSFNK RHRLADVVAD VCRFQSSSYE MQSNTDLQSY 960 ILHRCRFVNQ DLSYLFDKSL SLEPRSS 988 |
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| Keyword | KW-0159--Chromosome partition |
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| Interpro | IPR000651--Ras-like_Gua-exchang_fac_N |
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| PROSITE | |||||||||
| Pfam | |||||||||
| Gene Ontology | GO:0005829--C:cytosol |