dbPAF Protein Information

Tag Content
dbPAF ID dbPAF-0040843
Uniprot Accession Q9UST8; RNH1_SCHPO; O42798;
Genbank Protein ID NP_596126.1;
Genbank Nucleotide ID NM_001022044.2;
Protein Name Ribonuclease H
Protein Synonyms/Alias
Gene Name rnh1
Gene Synonyms/Alias SPBC336.06c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)		 Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Phosphorylation Sites
 dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
97DKYRKKISRSYSTEKdbPTM 3.0;UniProt;curated18257517; 16381945; 23193290; 22817900
102KISRSYSTEKDIEIFcurated22817900
Sequence
(Fasta)		MGGNKRAYYA VARGRNTGIY STWDEASDQV KGYGGNRYKK FDSYEAAQEF CRTEGSRYSS 60
SSGPYRRSTT SYGYSPYSSS SSNYSARHSD KYRKKISRSY STEKDIEIFS NDTHEKSIAC 120
SDRQVVYADG SSLRNGKKGA VAGCGVFFGN DDPRNISVPL AGEEQTNNRA ELQAIILALE 180
NTSGDLTIRS DSNYSIKSLT TWLPKWKKND FKTSNSQPVK NLDLINRASD LMSDRNVSLE 240
YVKGHSTDYG NQQADMLARR GASE 265
Keyword

KW-0181--Complete proteome
KW-0255--Endonuclease
KW-0378--Hydrolase
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0540--Nuclease
KW-0597--Phosphoprotein
KW-1185--Reference proteome
Interpro

IPR009027--Ribosomal_L9/RNase_H1_N
IPR017067--RNase_H1_euk
IPR011320--RNase_H1_N
IPR012337--RNaseH-like_dom
IPR002156--RNaseH_domain
PROSITE

PS50879--RNASE_H
Pfam

PF01693--Cauli_VI
PF00075--RNase_H
Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0000287--F:magnesium ion binding
GO:0003676--F:nucleic acid binding
GO:0004523--F:RNA-DNA hybrid ribonuclease activity
GO:0043137--P:DNA replication, removal of RNA primer
GO:0006401--P:RNA catabolic process
GO:0090502--P:RNA phosphodiester bond hydrolysis, endonucleolytic