dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040831
Uniprot Accession Q9USL4; NUP61_SCHPO; Q9UTW5;
Genbank Protein ID NP_587937.2;
Genbank Nucleotide ID NM_001022928.2;
Protein Name Nucleoporin nup61
Protein Synonyms/Alias Nuclear pore protein nup61;
Gene Name nup61
Gene Synonyms/Alias SPCC18B5.07c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. May play a role in mitotic spindle formation and/or function.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
17LTKDQDDSDDDRHGPdbPTM 3.0;SysPTM 2.0;UniProt;curated18257517; 16381945; 23193290; 19366988; 22817900
346FTFTNPLSSKKLPAScurated22817900
347TFTNPLSSKKLPASSdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MSKRGADHQL TKDQDDSDDD RHGPVEVPKE ASADVMATRK IAKPKSRKRP TSGVSSPGIF 60
ANLAAKPVSL PASTTQFTFG KPAVTANNDS DIHLKKRGLN KSFIDAVIKS VDNNPFGNLS 120
PLFDEYRQHF SSIEKKPAEE QPTSNAVVSE VNPQQQKSQD SSSFVTEKPA SSEKEDKEKP 180
LVPPGAPRFG FSAPALGSSF QFNSSAFTPK GSFGEKSATE AEAKEKETSS NQTATGTAAT 240
TTNQFSFNTA ANPFAFAKKE NEESKPLTPV FSFSTTMASA DASKETKQTH ETKDSKSEES 300
KPSNNEKSEN AVEPAKGNTM SFSWTPDKPI KFDTPEKKFT FTNPLSSKKL PASSDVKPPS 360
AAAVGFSFGT TTNPFSFAAP KSSFPTSSTP ASVGAEKSEE TSNGNKSEQE EKENGNDETR 420
SNDSLVSGKG KGEENEDSVF ETRAKIYRFD ATSKSYSDIG IGPLKINVDR DTGSARILAR 480
VEGSGKLLLN VRLCQDFEYS LAGKKDVKVP AASTDGKSIE MYLIRVKEPS TAEKLLAELN 540
EKKVSKSEN
Keyword

KW-0181--Complete proteome
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0811--Translocation
KW-0813--Transport

Interpro

IPR015007--NUP2/50/61
IPR011993--PH/PTB_dom
IPR000156--Ran_bind_dom

PROSITE

PS50196--RANBD1

Pfam

PF08911--NUP50
PF00638--Ran_BP1

Gene Ontology

GO:0034399--C:nuclear periphery
GO:0005643--C:nuclear pore
GO:0005634--C:nucleus
GO:0051028--P:mRNA transport
GO:0006913--P:nucleocytoplasmic transport
GO:0015031--P:protein transport