dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040829
Uniprot Accession Q9USK0; IPK1_SCHPO; P78889;
Genbank Protein ID NP_588080.1;
Genbank Nucleotide ID NM_001023072.2;
Protein Name Inositol-pentakisphosphate 2-kinase
Protein Synonyms/Alias Inositol-1,3,4,5,6-pentakisphosphate 2-kinase;Ins(1,3,4,5,6)P5 2-kinase;InsP5 2-kinase;
Gene Name ipk1
Gene Synonyms/Alias SPCC4B3.10c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
370FKSPAPYSPTSVISNcurated22817900
372SPAPYSPTSVISNHSdbPTM 3.0;UniProt18257517; 16381945; 23193290
Sequence
(Fasta)
MPLKNYTKTT SKKEPKQLDI AASDQQIEQW SDQIHKLDKA IRSTIDNSRL FYDAWRCMVC 60
IAPSVTASWI SLYRQLPPEK QPAASVGTLV DWNKALERQR REVLLALQNF HVIVIAPCKE 120
VKGYVKKAVE MIKRRDKKVK ELEKIQKELL VVYELPDPET KKSKIKALQS QLVRVNGELD 180
DLQKHLTLSF PTLIAKSRVF FGQLMKHFYC LQLQMFRKMH NIVRPWDCFQ DDIPQTWLVE 240
FSSVCQAAES ISLIAVNNNR PPVELPKSGD VLSNREWEAG KIDAMNSLIA QNLHTSASQV 300
SLSPMASTAS SSVTNSPVDT HTPSTPIMSR PPSMKALSSG VESQDESVAS SNFQVPIISN 360
PLFKSPAPYS PTSVISNHSS TGKSLVISEW AYLASGSANV VFEYVGKNPY FQDKVIRLRR 420
RGQVFTTEQV YEYYQNVIYP LFAGMESFLI EVFLQPVTRD FLLAAQNASG IYLNLNEQYC 480
LVMKDLKDGI EMKPKWLTQS PAAPPDWVVC RTCALSRMRG RPVGFCPLQL DFNNWPKFLC 540
CLQGFVSPDI AMRLFQSGIL RKLRDLQEQY SRTDVALAMT LRDVTLYIGK DHITLLDLDP 600
KDMNTKMSKW ERDERNLIEG GWYYGRGMKS TDKACRSSIK 641
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR027267--AH/BAR-dom
IPR009286--Ins_P5_2-kin

PROSITE
Pfam

PF06090--Ins_P5_2-kin

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0035299--F:inositol pentakisphosphate 2-kinase activity
GO:0032958--P:inositol phosphate biosynthetic process