dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040820
Uniprot Accession Q9US54; TAF11_SCHPO;
Genbank Protein ID NP_593491.1;
Genbank Nucleotide ID NM_001018925.2;
Protein Name Transcription initiation factor TFIID subunit 11
Protein Synonyms/Alias TBP-associated factor 11;
Gene Name taf11
Gene Synonyms/Alias SPAC1002.04c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription (By similarity).
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
37HAKANTASPAAEPAPdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MKRTGSASSV PRFQRSMSYD QSNSPTAGAH AKANTASPAA EPAPSSKEKE NWNRQEENDL 60
EEDDRDDFGT AAISKVAGKP GETDDEANEK LRTKYLLESF DEEQMQRYEV FRRANLNKTN 120
VKKLANQILN QSVTPNVAIV ISGFSKVFVG EIVELARKIQ DQWGDTGPLS PDHLREAYRL 180
SRQNRRLYPQ SRHVSHLFR
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR009072--Histone-fold
IPR006809--TAFII28

PROSITE
Pfam

PF04719--TAFII28

Gene Ontology

GO:0005829--C:cytosol
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0005669--C:transcription factor TFIID complex
GO:0003713--F:transcription coactivator activity
GO:0000991--F:transcription factor activity, core RNA polymerase II binding
GO:0008134--F:transcription factor binding
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0051123--P:RNA polymerase II transcriptional preinitiation complex assembly
GO:0006367--P:transcription initiation from RNA polymerase II promoter