| Tag |
Content |
| dbPAF ID |
dbPAF-0040818 |
| Uniprot Accession |
Q9US25; HRP1_SCHPO; Q92369; Q9UU28;
|
| Genbank Protein ID |
NP_593660.1;
|
| Genbank Nucleotide ID |
NM_001019092.2;
|
| Protein Name |
Chromodomain helicase hrp1 |
| Protein Synonyms/Alias |
ATP-dependent helicase hrp1; |
| Gene Name |
hrp1 |
| Gene Synonyms/Alias |
SPAC1783.05; |
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity.Functional Description
Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity. |
Phosphorylation Sites
|
dbPAF PTMs: 5 |
Sequence
(Fasta) | MEPEHSNYDL KNHPTSVQES TLNGSAVTDP QFGNTTNSLP SMNGLLNHEN SFASQQSLSS 60
SAFDDSEIVT STANSTVVSS ALSTPKIDDA QNSDDVRVDG TRRSSRAKRP VYRDFSYTEI 120
DEHEIPIPKK RKSKPAPKQK KSVASDDEDA YDKRHRFSIN SASGTEIRTS LRSSKGKSVN 180
YNEQEFYDDF EDEEEEVEEQ VEEEYEPIID FVLNHRKRAD AQDDDPKSSY QYLIKWQEVS 240
HLHNTWEDYS TLSSVRGYKK VDNYIKQNII YDREIREDPT TTFEDIEALD IERERKNMLF 300
EEYKIVERIV ASETNEEGKT EYFVKWRQLP YDNCTWEDAD VIYSMAPNEV YQFLQRENSP 360
YLPYKGVFYN TRPPYRKLEK QPSYIKGGEI RDFQLTGINW MAYLWHRNEN GILADEMGLG 420
KTVQTVCFLS YLVHSLKQHG PFLIVVPLST VPAWQETLAN WTPDLNSICY TGNTESRANI 480
REYEFYLSTN SRKLKFNILL TTYEYILKDK QELNNIRWQY LAIDEAHRLK NSESSLYETL 540
SQFRTANRLL ITGTPLQNNL KELASLVNFL MPGKFYIRDE LNFDQPNAEQ ERDIRDLQER 600
LQPFILRRLK KDVEKSLPSK SERILRVELS DMQTEWYKNI LTKNYRALTG HTDGRGQLSL 660
LNIVVELKKV SNHPYLFPGA AEKWMMGRKM TREDTLRGII MNSGKMVLLD KLLQRLKHDG 720
HRVLIFSQMV RMLNILGEYM SLRGYNYQRL DGTIPASVRR VSIDHFNAPD SPDFVFLLST 780
RAGGLGINLN TADTVIIFDS DWNPQADLQA MARAHRIGQK NHVNVYRFLS KDTVEEDILE 840
RARRKMILEY AIISLGVTEK SKNSKNDKYD AQELSAILKF GASNMFKATE NQKKLENMNL 900
DDILSHAEDR DSSNDVGGAS MGGEEFLKQF EVTDYKAEDL NWDDIIPEEE MERIEEEERM 960
LAAQRAKEEE RERREEEERE NDEDHPSRTY KRTTKSITKR QQRREEMVRE KEIRLLYRAM 1020
IKFGLVDERF DTIVKEAELQ ATDPKRIYSL SADMVKACDE AVERLGADDT KNKQPRKAIL 1080
IEFKGVKNIN AETVTLRVKD LTHLHRAYKG LDPLKQIIGY PIRSVHSWNC SWGIKEDSML 1140
LAGINKHGFG CWQAIKNDPD LGLHDKIFLD EAKNDKESRY VPSAVHLVRR GEYLLSVVRE 1200
HPDLFVVKTD QPTKRKYNRK APTKSSTRQT TLDGSISNTK KSSRTKKKKE EETNRGDETS 1260
PEGTVGEDEV EEEPRQAEPP KRALRSNSGK AASNKRTTRN SMKTHSAMDT LTAVAALDAE 1320
LDNMSNEKAK EEVDHVKSEN GESVNEPNTE DLSLETEENT TVSDISPLVK NEA
1374Fasta Sequence
>Q9US25|hrp1|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MEPEHSNYDLKNHPTSVQESTLNGSAVTDPQFGNTTNSLPSMNGLLNHENSFASQQSLSSSAFDDSEIVTSTANSTVVSSALSTPKIDDAQNSDDVRVDGTRRSSRAKRPVYRDFSYTEIDEHEIPIPKKRKSKPAPKQKKSVASDDEDAYDKRHRFSINSASGTEIRTSLRSSKGKSVNYNEQEFYDDFEDEEEEVEEQVEEEYEPIIDFVLNHRKRADAQDDDPKSSYQYLIKWQEVSHLHNTWEDYSTLSSVRGYKKVDNYIKQNIIYDREIREDPTTTFEDIEALDIERERKNMLFEEYKIVERIVASETNEEGKTEYFVKWRQLPYDNCTWEDADVIYSMAPNEVYQFLQRENSPYLPYKGVFYNTRPPYRKLEKQPSYIKGGEIRDFQLTGINWMAYLWHRNENGILADEMGLGKTVQTVCFLSYLVHSLKQHGPFLIVVPLSTVPAWQETLANWTPDLNSICYTGNTESRANIREYEFYLSTNSRKLKFNILLTTYEYILKDKQELNNIRWQYLAIDEAHRLKNSESSLYETLSQFRTANRLLITGTPLQNNLKELASLVNFLMPGKFYIRDELNFDQPNAEQERDIRDLQERLQPFILRRLKKDVEKSLPSKSERILRVELSDMQTEWYKNILTKNYRALTGHTDGRGQLSLLNIVVELKKVSNHPYLFPGAAEKWMMGRKMTREDTLRGIIMNSGKMVLLDKLLQRLKHDGHRVLIFSQMVRMLNILGEYMSLRGYNYQRLDGTIPASVRRVSIDHFNAPDSPDFVFLLSTRAGGLGINLNTADTVIIFDSDWNPQADLQAMARAHRIGQKNHVNVYRFLSKDTVEEDILERARRKMILEYAIISLGVTEKSKNSKNDKYDAQELSAILKFGASNMFKATENQKKLENMNLDDILSHAEDRDSSNDVGGASMGGEEFLKQFEVTDYKAEDLNWDDIIPEEEMERIEEEERMLAAQRAKEEERERREEEERENDEDHPSRTYKRTTKSITKRQQRREEMVREKEIRLLYRAMIKFGLVDERFDTIVKEAELQATDPKRIYSLSADMVKACDEAVERLGADDTKNKQPRKAILIEFKGVKNINAETVTLRVKDLTHLHRAYKGLDPLKQIIGYPIRSVHSWNCSWGIKEDSMLLAGINKHGFGCWQAIKNDPDLGLHDKIFLDEAKNDKESRYVPSAVHLVRRGEYLLSVVREHPDLFVVKTDQPTKRKYNRKAPTKSSTRQTTLDGSISNTKKSSRTKKKKEEETNRGDETSPEGTVGEDEVEEEPRQAEPPKRALRSNSGKAASNKRTTRNSMKTHSAMDTLTAVAALDAELDNMSNEKAKEEVDHVKSENGESVNEPNTEDLSLETEENTTVSDISPLVKNEA
|
| Keyword |
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
|
| Interpro |
IPR000953--Chromo/shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
|
| PROSITE |
PS50013--CHROMO_2
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
|
| Pfam |
PF00385--Chromo
PF00271--Helicase_C
PF00176--SNF2_N
|
| Gene Ontology |
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0016592--C:mediator complex
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0003677--F:DNA binding
GO:0008094--F:DNA-dependent ATPase activity
GO:0006338--P:chromatin remodeling
GO:0030702--P:chromatin silencing at centromere
GO:1990141--P:chromatin silencing at centromere outer repeat region
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0048096--P:chromatin-mediated maintenance of transcription
GO:0032508--P:DNA duplex unwinding
GO:0007076--P:mitotic chromosome condensation
GO:0035067--P:negative regulation of histone acetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0060303--P:regulation of nucleosome density
GO:0006369--P:termination of RNA polymerase II transcription
|
