dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040805
Uniprot Accession Q9URW7; VPS17_SCHPO;
Genbank Protein ID NP_593047.1;
Genbank Nucleotide ID NM_001018446.2;
Protein Name Vacuolar protein sorting-associated protein 17
Protein Synonyms/Alias
Gene Name vps17
Gene Synonyms/Alias SPAPJ696.01c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor pep1/vps10. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The vps29-vps26-vps35 subcomplex may be involved in cargo selection.
Phosphorylation Sites
dbPAF PTMs: 2
PositionPeptidesSourceReferences ( PMIDs )
7-MSSQHSTDDLMNSHcurated22817900
476EEYPRRLSNPPPSQKdbPTM 3.0;SysPTM 2.0;curated18257517; 16381945; 23193290; 19366988; 22817900
Sequence
(Fasta)
MSSQHSTDDL MNSHVFSGGF STLDDKGFQD VPIHTDMPGS ISVEPSSEDA NVGSVNGNIN 60
ETPVFEADRL IAEATMNPSA ASSTTGENSI SQTGSGPFLR IRIVDIEAEN SKDPVIKMNV 120
QTTLPAYRSK LYKNVRRTHA EFKKFAKYLI STHPECLIPA VPEAKTSVSS GIKEDLIYLK 180
SGLQSWLNYV STNPNLLYDP ELQLFVESDY GYSPLINTGN PTSGLKRKAL KQFPLPPDPC 240
QALANLRPIV KSFYKNAKDA EIKLEKLVNR KQSLALTHAD LGQSLIDYSV EEQHNGLANA 300
LNRVGKMLQA ISDVRIMQSS KQLVTLADSL CYASDNAFVV KEILSNRHIL MRDLISSKNQ 360
TNSYLSAANR LQDSPKISKA RTDDALQALE VARVHEKLLS DKVDFVTLNL VKESKTYTKK 420
TSVSLQKAIR EYVEKEAYYE RRLLSIMESI RPHIRNIDPF GGLSRLGREE YPRRLSNPPP 480
SQKTNQDAWT NRKRPGYSSS FDGSSQSTFN PSNNDGAHNT SENADELVEP PIGNERLDPK 540
SVANLLNAI
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR001683--Phox
IPR014461--Retromer_complex_Vps17

PROSITE
Pfam

PF00787--PX

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0019898--C:extrinsic component of membrane
GO:0005634--C:nucleus
GO:0005628--C:prospore membrane
GO:0030904--C:retromer complex
GO:0035091--F:phosphatidylinositol binding
GO:0032120--P:ascospore-type prospore membrane assembly
GO:0006897--P:endocytosis
GO:0006886--P:intracellular protein transport
GO:0042147--P:retrograde transport, endosome to Golgi
GO:0016050--P:vesicle organization
GO:0016192--P:vesicle-mediated transport