dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040803
Uniprot Accession Q9URV9; SRX1_SCHPO;
Genbank Protein ID NP_595151.1;
Genbank Nucleotide ID NM_001021060.2;
Protein Name Sulfiredoxin
Protein Synonyms/Alias
Gene Name srx1
Gene Synonyms/Alias SPBC106.02c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in a peroxiredoxin. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
105RCKLVNCSPNTLRLYcurated22817900
Sequence
(Fasta)
MTSIHTGSNN NIVELDMSEL IRPIPPVLDM NKVNSMMETM TGKTPPASCG LTSEDLEAGE 60
LPPVDVLTFK KSGKPYYFAF GGCHRLRAHD EAGRKKVRCK LVNCSPNTLR LYLGASANKF 120
LDSD 125
Keyword

KW-0049--Antioxidant
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1015--Disulfide bond
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0560--Oxidoreductase
KW-1185--Reference proteome

Interpro

IPR003115--ParB/Sulfiredoxin_dom
IPR016692--Sulfiredoxin

PROSITE
Pfam

PF02195--ParBc

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0032542--F:sulfiredoxin activity
GO:0034613--P:cellular protein localization
GO:0034599--P:cellular response to oxidative stress
GO:0098754--P:detoxification