dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0040795
Uniprot Accession Q9URM2; TKT_SCHPO; P78824;
Genbank Protein ID NP_596066.1;
Genbank Nucleotide ID NM_001021977.2;
Protein Name Probable transketolase
Protein Synonyms/Alias
Gene Name SPBC2G5.05
Gene Synonyms/Alias
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
11SSYTDIDTLAINTIRcurated22817900
Sequence
(Fasta)
MTSSSYTDID TLAINTIRTL AVDTTAHAKS GHPGAPMGLA PAAHVLFSRI MKFNPAHPKW 60
LNRDRFILSN GHACVLQYIM CHLLGYKLTI EDLKQFRQVG SKTPGHPETH NPDLNIETGA 120
GPLGQGIASA VGLAIGKAHS AAVYNKPGFD LFSNYTFCFL GDGCLQEGVS SEACSLAGHL 180
KLSNLIAVWD NNKITIDGAT SMSFDEDVEK RFEAYGWNIV RVANGDTDLD GIEKGFREAM 240
SCTDKPTLIN LKTTIGYGSE LQGTHSVHGS PLKPEDCVHV KKLFGFDPTK TFQVPPEVYA 300
YYKERVAIAS SAEEEYKKMY ASYKQSYPDL SNQLERILSR KFPEGWEKHL PVYKPGDKAV 360
ATRKLSEIVL DALCPVLPEL VGGSADLTPS NLTRWEGAAD FQPPSSKLGT YAGRYIRYGI 420
REHGMAGIMN GLAVYGPIIP YGGTFLNFVS YAAGAVRMAA LNNSRVIYVA THDSIGLGED 480
GPTHQPIETF AHFRAMPNIN CWRPADGNET SAAYYSALTS DSTPSILALT RQNLPQLENS 540
TIENALKGGY VMLENKEADI TLVGTGSEVS LCIDTVKTLE TEYNLKARVV SLPCWEVFEQ 600
QPESYRLSVI PDGIPAMSVE VWATNGWRRY VHEAFGMHTF GDSGPAPKLY EKFHFTTSGV 660
AQRAKKTVDA YKDIPYIRSP VRRAF 686
Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-0460--Magnesium
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0786--Thiamine pyrophosphate
KW-0808--Transferase

Interpro

IPR029061--THDP-binding
IPR009014--Transketo_C/Pyr-ferredox_oxred
IPR005475--Transketolase-like_Pyr-bd
IPR005478--Transketolase_bac-like
IPR020826--Transketolase_BS
IPR005474--Transketolase_N

PROSITE

PS00801--TRANSKETOLASE_1
PS00802--TRANSKETOLASE_2

Pfam

PF02779--Transket_pyr
PF02780--Transketolase_C
PF00456--Transketolase_N

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0046872--F:metal ion binding
GO:0004802--F:transketolase activity
GO:0009052--P:pentose-phosphate shunt, non-oxidative branch