dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0039475
Uniprot Accession Q9P7X2; ELL1_SCHPO;
Genbank Protein ID NP_595826.1;
Genbank Nucleotide ID NM_001021730.2;
Protein Name RNA polymerase II elongation factor ell1
Protein Synonyms/Alias
Gene Name ell1
Gene Synonyms/Alias SPBP23A10.14c;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Activates transcription elongation by RNA polymerase II and pyrophosphorolysis as a complex with eaf1. Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
351RIPKLNASNYSPLLScurated22817900
358SNYSPLLSPSSHRKTcurated22817900
417HIKRKSRSPPQSLPScurated22817900
Sequence
(Fasta)
MIRNSSISDA LPVALGGNEE ESPLLMLVQL PKEFLEGYLS GTITDVSLEC SDVGTSILAN 60
DRSYKCTSVP ETAPHEIYRL VDSNSLQLVG RVSQKLQLRR ELDSLTAERV KNRTQEAQKE 120
KEEKRIVTLQ NDGGSKNTTA RKQKQLKKNG LRPLNTSASR IGLSSSPTNT PSPNLPVSQP 180
SASPHYSGDK NSAKGIDLRT RVIQLLAIAP ETEDFLRLRT KASLSKLQAL LPEVAWKNNM 240
NQWELLNPVY KDVRVFDWRP YSIADRNAVL SRMSNAFDNM QLPPDAPERS LLVSKQKNIT 300
KLNNEKRIPP QLAQPTSHVP SFIDTNSPSM PSISSVSSYQ QQHRIPKLNA SNYSPLLSPS 360
SHRKTSGNLS RTGSESSAVS LSDTTNLNTP ISDIPSPGSS TTCSNLSSPH IKRKSRSPPQ 420
SLPSTPFPTS SSSTNGTLEP NANSPKKNEQ DAWIAKKRRQ QRYTTEEMRA LAKRFRETYP 480
RYKNLYLKVS SYYDNNDTNN PNLNKLQDEL ISLHSQLKSW KNTLYDASSE LAL 534
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR011991--WHTH_DNA-bd_dom

PROSITE
Pfam
Gene Ontology

GO:0005829--C:cytosol
GO:0032783--C:ELL-EAF complex
GO:0005634--C:nucleus
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006368--P:transcription elongation from RNA polymerase II promoter