dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0039473
Uniprot Accession Q9P7W5; RIO2_SCHPO;
Genbank Protein ID NP_596200.2;
Genbank Nucleotide ID NM_001022119.2;
Protein Name Serine/threonine-protein kinase rio2
Protein Synonyms/Alias
Gene Name rio2
Gene Synonyms/Alias SPBC1703.05;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Required for the final endonucleolytic cleavage of 20S pre-rRNA at site D in the cytoplasm, converting it into the mature 18S rRNA. Involved in normal export of the pre-40S particles from the nucleus to the cytoplasm (By similarity).
Phosphorylation Sites
dbPAF PTMs: 1
PositionPeptidesSourceReferences ( PMIDs )
333KENGDDLSDNYEEEEcurated22817900
Sequence
(Fasta)
MVNLNIKAMR YLSAEDFRTL TAVEMGSRNH EVVPTNMINQ IAKIRGGSCT KSLSVLFMHK 60
LIAKVPHISY EGYRLTYAGY DYLALKALSK RASVYSVGNQ IGVGKESDVY VVGDQKGKQY 120
ILKIHRLGRI SFRSVKNNRD YLRNRKTGSW QYLSRLAATK EFAFMKILHE HGFPVPAPID 180
HSRHCIIMEM IDAFPLRAVT DIRDPPALYQ TLMDIIVRFA RNGLIHGDFN EFNIIVREDG 240
TAVVIDFPQM VSTSHPDAQF YFDRDVQCIV QYFEKNYQYK GDVPNFEDIS KMEKENNLDI 300
MIEASGFNKK QSKELEKYRQ EEEKRKENGD DLSDNYEEEE EEKE 345
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0418--Kinase
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0690--Ribosome biogenesis
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR030484--Rio2
IPR015285--RIO2_wHTH_N
IPR018935--RIO_kinase_CS
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01245--RIO1

Pfam

PF09202--Rio2_N

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0030490--P:maturation of SSU-rRNA