| Tag |
Content |
| dbPAF ID |
dbPAF-0039472 |
| Uniprot Accession |
Q9P7W3; ACL1_SCHPO; P78844;
|
| Genbank Protein ID |
NP_596202.1;
|
| Genbank Nucleotide ID |
NM_001022121.2;
|
| Protein Name |
Probable ATP-citrate synthase subunit 1 |
| Protein Synonyms/Alias |
ATP-citrate (pro-S-)-lyase 1;Citrate cleavage enzyme subunit 1; |
| Gene Name |
SPBC1703.07 |
| Gene Synonyms/Alias |
|
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols.Functional Description
Catalyzes the formation of cytosolic acetyl-CoA, which is mainly used for the biosynthesis of fatty acids and sterols. |
Phosphorylation Sites
|
dbPAF PTMs: 2 |
Sequence
(Fasta) | MAGSVDKPSY ELFSKDTRAF VYGMQTKAVQ GMLDFDYMCG RTVPSVAAII YTFGSQSISK 60
LYWGTKEILL PVYRTIEEAC TKHPEVDVVV NFASSRSAYA STMELMEFPQ IRCIAIIAEG 120
VPERRAREIL VTSKEKNVVI IGPATVGGIK PGCFKIGNTG GMMDNIVASK LYRPGSVAYV 180
SKSGGMSNEL NNIISHTTDG VYEGIAIGGD RYPGTTFIDH LIRFEADPAC KLMVLLGEVG 240
GVEEYRVIEA VKNGTIKKPI VAWAIGTCSS MFKTEVQFGH AGSFANSELE TAVAKNQAMR 300
EAGIYVPETF EKLPALLQEV YEGLVKKGVI VPQPEVAPPN IPLDYAWAKE LGLVRKPSSF 360
ICTISNDRGS ELTYNNVPIS KVFEEELGIG GVISLLWLRR RLPSYATKFL EMVLQLTADH 420
GPCVSGAMNT IITTRAGKDL ISSLVAGLLT IGTRFGGALD GAAQEFSKAY DAGLSPRAFV 480
DSCRKANKLI PGIGHRIKSR NNPDLRVELV KGYVKKNFPS TKLLDYALAV ENVTTSKKDN 540
LILNVDGCIA VCFVDLLRNC GAFTLEEANE YINLGILNGM FVLGRSIGLI GHHLDQKRLR 600
APLYRHPWDD FLYLS
616Fasta Sequence
>Q9P7W3|SPBC1703.07|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MAGSVDKPSYELFSKDTRAFVYGMQTKAVQGMLDFDYMCGRTVPSVAAIIYTFGSQSISKLYWGTKEILLPVYRTIEEACTKHPEVDVVVNFASSRSAYASTMELMEFPQIRCIAIIAEGVPERRAREILVTSKEKNVVIIGPATVGGIKPGCFKIGNTGGMMDNIVASKLYRPGSVAYVSKSGGMSNELNNIISHTTDGVYEGIAIGGDRYPGTTFIDHLIRFEADPACKLMVLLGEVGGVEEYRVIEAVKNGTIKKPIVAWAIGTCSSMFKTEVQFGHAGSFANSELETAVAKNQAMREAGIYVPETFEKLPALLQEVYEGLVKKGVIVPQPEVAPPNIPLDYAWAKELGLVRKPSSFICTISNDRGSELTYNNVPISKVFEEELGIGGVISLLWLRRRLPSYATKFLEMVLQLTADHGPCVSGAMNTIITTRAGKDLISSLVAGLLTIGTRFGGALDGAAQEFSKAYDAGLSPRAFVDSCRKANKLIPGIGHRIKSRNNPDLRVELVKGYVKKNFPSTKLLDYALAVENVTTSKKDNLILNVDGCIAVCFVDLLRNCGAFTLEEANEYINLGILNGMFVLGRSIGLIGHHLDQKRLRAPLYRHPWDDFLYLS
|
| Keyword |
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0460--Magnesium
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
|
| Interpro |
IPR016142--Citrate_synth-like_lrg_a-sub
IPR016143--Citrate_synth-like_sm_a-sub
IPR002020--Citrate_synthase
IPR003781--CoA-bd
IPR005810--CoA_lig_alpha
IPR005811--CoA_ligase
IPR016040--NAD(P)-bd_dom
IPR017866--Succ-CoA_synthase_bsu_CS
IPR016102--Succinyl-CoA_synth-like
|
| PROSITE |
PS01216--SUCCINYL_COA_LIG_1
PS01217--SUCCINYL_COA_LIG_3
|
| Pfam |
PF00285--Citrate_synt
PF02629--CoA_binding
PF00549--Ligase_CoA
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0003878--F:ATP citrate synthase activity
GO:0048037--F:cofactor binding
GO:0046872--F:metal ion binding
GO:0006085--P:acetyl-CoA biosynthetic process
GO:0006101--P:citrate metabolic process
GO:0006091--P:generation of precursor metabolites and energy
GO:0006629--P:lipid metabolic process
|
