| Tag |
Content |
| dbPAF ID |
dbPAF-0039460 |
| Uniprot Accession |
Q9P7Q4; SEC18_SCHPO;
|
| Genbank Protein ID |
NP_594690.1;
|
| Genbank Nucleotide ID |
NM_001020119.2;
|
| Protein Name |
Vesicular-fusion protein sec18 |
| Protein Synonyms/Alias |
|
| Gene Name |
sec18 |
| Gene Synonyms/Alias |
SPAC1834.11c; |
| Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
| NCBI Taxa ID |
284812 |
Functional Description
(View all) |
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity).Functional Description
Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin (By similarity). |
Phosphorylation Sites
|
dbPAF PTMs: 3 |
Sequence
(Fasta) | MDSRWKLPFM SNKGTPEQPM RKPLSGSYSH NSAGPTPNMS PFEQKPPLPT HMDVRRPSGP 60
FRIVKATSTE DALTNCIIVS PMDFKQQYII VDNSRVFSTK PVPGFPQGCL GASQPHREWA 120
SWSLNQQVHV ADYDPYGPHG APYLHSMTLE VDFQNRNRTT NEPFDGEEMA KLFCSSYQSQ 180
VFSPGQKIVF DFRSYNIKAT VRTISCVDLL IGENQDAENT ADTSKRGLLT SQTEIQFFKA 240
AHSALRLKAS MTRPASNAIL QPGFKFEDMG IGGLDSEFSA IFRRAFASRL FPPGMVEKLG 300
INHVKGILLY GPPGTGKTLI ARQIGKMLNA REPKIVNGPE ILNKYVGQSE ENVRKLFADA 360
EREYRDRGEE SGLHIIIFDE LDAICKKRGS SGGDTGVGDQ VVNQLLAKMD GVDQLNNILV 420
IGMTNRKDMI DEALLRPGRL EVHMEISLPD EHGRLQILKI HTSRMASNGI LENDVDMEEL 480
ASLTKNFSGA EIAGLIKSAS SFAFYRHIKV GTTAAVSGNL ENIKVNRNDF LNALSEVRPA 540
YGVSEEELES RVQGGIINFG KHIEEIITEG KLFVQQVKNS ERTRLVSVLL SGPIASGKTA 600
LAATIALGSE FPFVKLVSAE SMVGMNENAR VAHVNRVFED SYKSPLSVIV VDEIERIIDW 660
VPIGPRFSNT LLQTLMVLFK KQPPKGHRLL ILATTSERTM LSRMDMTQSF DAEIAVPNVS 720
NVTELDRIIQ SIDSFADSNV RADTLQRLQN FTGTDAVNVG VAKILMIAET AKQDVDVVSC 780
FVEAMARAIP ME
793Fasta Sequence
>Q9P7Q4|sec18|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
MDSRWKLPFMSNKGTPEQPMRKPLSGSYSHNSAGPTPNMSPFEQKPPLPTHMDVRRPSGPFRIVKATSTEDALTNCIIVSPMDFKQQYIIVDNSRVFSTKPVPGFPQGCLGASQPHREWASWSLNQQVHVADYDPYGPHGAPYLHSMTLEVDFQNRNRTTNEPFDGEEMAKLFCSSYQSQVFSPGQKIVFDFRSYNIKATVRTISCVDLLIGENQDAENTADTSKRGLLTSQTEIQFFKAAHSALRLKASMTRPASNAILQPGFKFEDMGIGGLDSEFSAIFRRAFASRLFPPGMVEKLGINHVKGILLYGPPGTGKTLIARQIGKMLNAREPKIVNGPEILNKYVGQSEENVRKLFADAEREYRDRGEESGLHIIIFDELDAICKKRGSSGGDTGVGDQVVNQLLAKMDGVDQLNNILVIGMTNRKDMIDEALLRPGRLEVHMEISLPDEHGRLQILKIHTSRMASNGILENDVDMEELASLTKNFSGAEIAGLIKSASSFAFYRHIKVGTTAAVSGNLENIKVNRNDFLNALSEVRPAYGVSEEELESRVQGGIINFGKHIEEIITEGKLFVQQVKNSERTRLVSVLLSGPIASGKTALAATIALGSEFPFVKLVSAESMVGMNENARVAHVNRVFEDSYKSPLSVIVVDEIERIIDWVPIGPRFSNTLLQTLMVLFKKQPPKGHRLLILATTSERTMLSRMDMTQSFDAEIAVPNVSNVTELDRIIQSIDSFADSNVRADTLQRLQNFTGTDAVNVGVAKILMIAETAKQDVDVVSCFVEAMARAIPME
|
| Keyword |
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
|
| Interpro |
IPR003593--AAA+_ATPase
IPR009010--Asp_de-COase-like_dom
IPR003959--ATPase_AAA_core
IPR003960--ATPase_AAA_CS
IPR004201--Cdc48_dom2
IPR029067--CDC48_domain_2-like
IPR003338--CDC4_N-term_subdom
IPR027417--P-loop_NTPase
|
| PROSITE |
PS00674--AAA
|
| Pfam |
PF00004--AAA
PF02933--CDC48_2
|
| Gene Ontology |
GO:0005737--C:cytoplasm
GO:0005795--C:Golgi stack
GO:0005524--F:ATP binding
GO:0016887--F:ATPase activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0048211--P:Golgi vesicle docking
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0042144--P:vacuole fusion, non-autophagic
|
