dbPAF Protein Information
| Tag | Content | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| dbPAF ID | dbPAF-0039458 | ||||||||||||
| Uniprot Accession | Q9P7M1; DEP1_SCHPO; Q9UTW6; Q9UTY3; | ||||||||||||
| Genbank Protein ID | NP_596582.1; | ||||||||||||
| Genbank Nucleotide ID | NM_001022502.2; | ||||||||||||
| Protein Name | Transcriptional regulatory protein dep1 | ||||||||||||
| Protein Synonyms/Alias | |||||||||||||
| Gene Name | dep1 | ||||||||||||
| Gene Synonyms/Alias | SPBC21C3.02c; | ||||||||||||
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) | ||||||||||||
| NCBI Taxa ID | 284812 | ||||||||||||
| Functional Description (View all) |
Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). | ||||||||||||
| Phosphorylation Sites |
dbPAF PTMs: 2
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| Sequence (Fasta) | MTENLQSESI PHEILPKEPF DLPMNNLKSS PKNKDSEKRI NNSIAESEQV VDSALSNPET 60 NANEDIIAPQ LPSQNSEIIE KNSPVNKLNS STSLTTHQLA SLPKLEVTDH DNVSEAETVV 120 LNEDEEKETS LVGSVSVTED LGDSSAIGRT ILVNNSVEPQ MENTANITIV SPSLKESDFE 180 SEEKATNDNN GLIETNHNSK LEESSEHEEE EDEESNIERT EDSDHQIPQR GGTLEAPRKG 240 GPRSGVGSRK RKRATVSRKW STNSESKIKR VALETSQEES DREIADRRSA SEQAHEADDE 300 KAIKRKEAFD ALLNIETEFT FLRNRLYGKK LLKLNEHEEM IQNETHERFN ACIDLITERR 360 DDRVRLATEN LMKQLGNIKN VMDYVTKQRK YQLLFDKRRI RQALLTKIAT KCFQLLNKQK 420 SVHDPTYITQ KTMSYRQSAL LQKQRIEYEA AVLCELNSFA GFPTAPIIET ASFDDIRNDL 480 LEMGCLSENQ D 492 |
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| Keyword | KW-0156--Chromatin regulator |
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| Interpro | IPR013907--Sds3 |
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| PROSITE | |||||||||||||
| Pfam | PF08598--Sds3 |
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| Gene Ontology | GO:0005634--C:nucleus |