Tag |
Content |
dbPAF ID |
dbPAF-0039454 |
Uniprot Accession |
Q9P7J8; GAD8_SCHPO; |
Genbank Protein ID |
NP_588010.1; |
Genbank Nucleotide ID |
NM_001023001.2; |
Protein Name |
Serine/threonine-protein kinase gad8 |
Protein Synonyms/Alias |
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Gene Name |
gad8 |
Gene Synonyms/Alias |
SPCC24B10.07; |
Organism |
Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) |
NCBI Taxa ID |
284812 |
Functional Description (View all) |
Involved in a signaling module for sexual development and cell growth under stressed conditions. Required for G1 arrest under nitrogen starvation and for growth at high temperature and osmolarity.Functional Description
Involved in a signaling module for sexual development and cell growth under stressed conditions. Required for G1 arrest under nitrogen starvation and for growth at high temperature and osmolarity.
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Phosphorylation Sites
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dbPAF PTMs: 3 |
Sequence (Fasta) | MSWKLTKKLK ETHLASAIGL NSGGSSFTRG LKNSTLSSTS SRKSSDEKSR KSSEDKRSPQ 60 STVVQPGLLQ VTIIEARNLK LPSGHVPANY GVSIDNSLLA PPLSNGSGHA RSRSHAWWLP 120 YIVVEFDKNE ILVDALNTAS LENPCWDYQA TFDVSRYSKL SLNIYLRSSS SRSRNGMGND 180 AFLGGIKLSP SFIVNKLTDE WVPLHGGSGE LRVQMLYKPN QSTPLTIDAF ELLKVVGKGS 240 FGKVMQVRKR DTSRIYALKT MKKAHIVSRS EVDHTLAERT VLAQVNNPFI VPLKFSFQSP 300 GKLYLVLAFV NGGELFHHLQ REGCFDTYRA KFYIAELLVA LECLHEFNVI YRDLKPENIL 360 LDYTGHIALC DFGLCKLNMA KTDRTNTFCG TPEYLAPELL LGHGYTKVVD WWTLGVLLYE 420 MITGLPPFYD ENINEMYRKI LQDPLRFPDN IDEKAKDLLS GLLTRAPEKR LGSGGAQEIK 480 NHPFFDDIDW KKLCAKKIQP PFKPSVESAI DTSNFDSEFT SEIPMDSVVA DSHLSETVQQ 540 RFANWSYQRP TTIDTSDDIN TIAPGSVIR
Fasta Sequence
>Q9P7J8|gad8|Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast) MSWKLTKKLKETHLASAIGLNSGGSSFTRGLKNSTLSSTSSRKSSDEKSRKSSEDKRSPQSTVVQPGLLQVTIIEARNLKLPSGHVPANYGVSIDNSLLAPPLSNGSGHARSRSHAWWLPYIVVEFDKNEILVDALNTASLENPCWDYQATFDVSRYSKLSLNIYLRSSSSRSRNGMGNDAFLGGIKLSPSFIVNKLTDEWVPLHGGSGELRVQMLYKPNQSTPLTIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAERTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELLVALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPELLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDLLSGLLTRAPEKRLGSGGAQEIKNHPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNFDSEFTSEIPMDSVVADSHLSETVQQRFANWSYQRPTTIDTSDDINTIAPGSVIR
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Keyword |
KW-0067--ATP-binding KW-0181--Complete proteome KW-0418--Kinase KW-0547--Nucleotide-binding KW-0597--Phosphoprotein KW-1185--Reference proteome KW-0723--Serine/threonine-protein kinase KW-0808--Transferase
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Interpro |
IPR000961--AGC-kinase_C IPR000008--C2_dom IPR011009--Kinase-like_dom IPR017892--Pkinase_C IPR000719--Prot_kinase_dom IPR017441--Protein_kinase_ATP_BS IPR002290--Ser/Thr_dual-sp_kinase IPR008271--Ser/Thr_kinase_AS
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PROSITE |
PS51285--AGC_KINASE_CTER PS00107--PROTEIN_KINASE_ATP PS50011--PROTEIN_KINASE_DOM PS00108--PROTEIN_KINASE_ST
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Pfam |
PF00168--C2 PF00069--Pkinase PF00433--Pkinase_C
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Gene Ontology |
GO:0005524--F:ATP binding GO:0004672--F:protein kinase activity GO:0004674--F:protein serine/threonine kinase activity GO:0030291--F:protein serine/threonine kinase inhibitor activity GO:0031142--P:induction of conjugation upon nitrogen starvation GO:0071901--P:negative regulation of protein serine/threonine kinase activity GO:1903940--P:negative regulation of TORC2 signaling GO:0018107--P:peptidyl-threonine phosphorylation GO:0031139--P:positive regulation of conjugation with cellular fusion
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