dbPAF Protein Information


Tag Content
dbPAF ID dbPAF-0039454
Uniprot Accession Q9P7J8; GAD8_SCHPO;
Genbank Protein ID NP_588010.1;
Genbank Nucleotide ID NM_001023001.2;
Protein Name Serine/threonine-protein kinase gad8
Protein Synonyms/Alias
Gene Name gad8
Gene Synonyms/Alias SPCC24B10.07;
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843)(Fission yeast)
NCBI Taxa ID 284812
Functional Description
(View all)
Involved in a signaling module for sexual development and cell growth under stressed conditions. Required for G1 arrest under nitrogen starvation and for growth at high temperature and osmolarity.
Phosphorylation Sites
dbPAF PTMs: 3
PositionPeptidesSourceReferences ( PMIDs )
387AKTDRTNTFCGTPEYdbPTM 3.0;UniProt12805221; 16381945; 23193290
527TSEIPMDSVVADSHLdbPTM 3.012805221; 16381945; 23193290
546QQRFANWSYQRPTTIdbPTM 3.012805221; 16381945; 23193290
Sequence
(Fasta)
MSWKLTKKLK ETHLASAIGL NSGGSSFTRG LKNSTLSSTS SRKSSDEKSR KSSEDKRSPQ 60
STVVQPGLLQ VTIIEARNLK LPSGHVPANY GVSIDNSLLA PPLSNGSGHA RSRSHAWWLP 120
YIVVEFDKNE ILVDALNTAS LENPCWDYQA TFDVSRYSKL SLNIYLRSSS SRSRNGMGND 180
AFLGGIKLSP SFIVNKLTDE WVPLHGGSGE LRVQMLYKPN QSTPLTIDAF ELLKVVGKGS 240
FGKVMQVRKR DTSRIYALKT MKKAHIVSRS EVDHTLAERT VLAQVNNPFI VPLKFSFQSP 300
GKLYLVLAFV NGGELFHHLQ REGCFDTYRA KFYIAELLVA LECLHEFNVI YRDLKPENIL 360
LDYTGHIALC DFGLCKLNMA KTDRTNTFCG TPEYLAPELL LGHGYTKVVD WWTLGVLLYE 420
MITGLPPFYD ENINEMYRKI LQDPLRFPDN IDEKAKDLLS GLLTRAPEKR LGSGGAQEIK 480
NHPFFDDIDW KKLCAKKIQP PFKPSVESAI DTSNFDSEFT SEIPMDSVVA DSHLSETVQQ 540
RFANWSYQRP TTIDTSDDIN TIAPGSVIR
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR000008--C2_dom
IPR011009--Kinase-like_dom
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR002290--Ser/Thr_dual-sp_kinase
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00168--C2
PF00069--Pkinase
PF00433--Pkinase_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0004672--F:protein kinase activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0030291--F:protein serine/threonine kinase inhibitor activity
GO:0031142--P:induction of conjugation upon nitrogen starvation
GO:0071901--P:negative regulation of protein serine/threonine kinase activity
GO:1903940--P:negative regulation of TORC2 signaling
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0031139--P:positive regulation of conjugation with cellular fusion